Evidence map›Paper›PMID 35252095›Full record

ArticleFrontiers in public health

Nipah Virus Outbreak in Kerala State, India Amidst of COVID-19 Pandemic.

Pragya D Yadav, Rima R Sahay, Anukumar Balakrishnan, Sreelekshmy Mohandas, Chandni Radhakrishnan, Mangesh D Gokhale, R Balasubramanian, Priya Abraham, Nivedita Gupta, A P Sugunan and 44 more

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In one paragraph

Article in Frontiers in public health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

54 authors at 5 institutions in 1 country.

Pragya D YadavIndian Council of Medical Research-National Institute of Virology, Pune, India.
Rima R SahayIndian Council of Medical Research-National Institute of Virology, Pune, India.
Anukumar BalakrishnanIndian Council of Medical Research-National Institute of Virology, Kerala Unit, Alappuzha, India.
Sreelekshmy MohandasIndian Council of Medical Research-National Institute of Virology, Pune, India.
Chandni RadhakrishnanDepartment of Medicine, Government Medical College, Kozhikode, India.
Mangesh D GokhaleIndian Council of Medical Research-National Institute of Virology, Pune, India.
R BalasubramanianIndian Council of Medical Research-National Institute of Virology, Kerala Unit, Alappuzha, India.
Priya AbrahamIndian Council of Medical Research-National Institute of Virology, Pune, India.
Nivedita GuptaEpidemiology and Communicable Diseases Division, Indian Council of Medical Research, New Delhi, India.
A P SugunanIndian Council of Medical Research-National Institute of Virology, Kerala Unit, Alappuzha, India.
Rajan KhobragadeHealth and Family Welfare Department, Government of Kerala, Thiruvananthapuram, India.
Kalpana GeorgeDepartment of Microbiology, Government Medical College, Kozhikode, India.
Anita SheteIndian Council of Medical Research-National Institute of Virology, Pune, India.
Savita PatilIndian Council of Medical Research-National Institute of Virology, Pune, India.
Ullas Padinjaremattathil ThankappanIndian Council of Medical Research-National Institute of Virology, Pune, India.
Hitesh DigheIndian Council of Medical Research-National Institute of Virology, Pune, India.
Jijo KoshyIndian Council of Medical Research-National Institute of Virology, Kerala Unit, Alappuzha, India.
Vivek VijayIndian Council of Medical Research-National Institute of Virology, Kerala Unit, Alappuzha, India.
R GayathriDepartment of Medicine, Government Medical College, Kozhikode, India.
P Jayesh KumarDepartment of Medicine, Government Medical College, Kozhikode, India.
Asma RahimDepartment of Community Medicine, Government Medical College, Kozhikode, India.
A NaveenNational Health Mission, Kozhikode, India.
Sarala NairHealth Department, Kozhikode, India.
V R RajendranGovernment Medical College, Kozhikode, India.
V JayasreeDistrict Medical Office of Health, Health Department, Kozhikode, India.
Triparna MajumdarIndian Council of Medical Research-National Institute of Virology, Pune, India.
Rajlaxmi JainIndian Council of Medical Research-National Institute of Virology, Pune, India.
Prasanth ViswanathanDepartment of Microbiology, Government Medical College, Kozhikode, India.
Deepak Y PatilIndian Council of Medical Research-National Institute of Virology, Pune, India.
Abhinendra KumarIndian Council of Medical Research-National Institute of Virology, Pune, India.
Dimpal A NyayanitIndian Council of Medical Research-National Institute of Virology, Pune, India.
Prasad SarkaleIndian Council of Medical Research-National Institute of Virology, Pune, India.
Ashwini WaghmareIndian Council of Medical Research-National Institute of Virology, Pune, India.
Shrikant BaradkarIndian Council of Medical Research-National Institute of Virology, Pune, India.
Pranita GawandeIndian Council of Medical Research-National Institute of Virology, Pune, India.
Poonam BodkeIndian Council of Medical Research-National Institute of Virology, Pune, India.
Kaumudi KaleleIndian Council of Medical Research-National Institute of Virology, Pune, India.
Jyoti YemulIndian Council of Medical Research-National Institute of Virology, Pune, India.
Sachin DhaigudeIndian Council of Medical Research-National Institute of Virology, Pune, India.
Manjunath HolepannawarIndian Council of Medical Research-National Institute of Virology, Pune, India.
Sanjay GopaleIndian Council of Medical Research-National Institute of Virology, Pune, India.
Ganesh ChopadeIndian Council of Medical Research-National Institute of Virology, Pune, India.
Shilpa RayIndian Council of Medical Research-National Institute of Virology, Pune, India.
Priyanka WaghmareIndian Council of Medical Research-National Institute of Virology, Pune, India.
Jitendra NarayanEpidemiology and Communicable Diseases Division, Indian Council of Medical Research, New Delhi, India.
Basavaraj MathapatiIndian Council of Medical Research-National Institute of Virology, Pune, India.
Manoj KadamIndian Council of Medical Research-National Institute of Virology, Pune, India.
Abhimanyu KumarIndian Council of Medical Research-National Institute of Virology, Pune, India.
Annasaheb SuryawanshiIndian Council of Medical Research-National Institute of Virology, Pune, India.
Beena Philomina JoseDepartment of Microbiology, Government Medical College, Kozhikode, India.
Saritha SivadasDepartment of Microbiology, Government Medical College, Kozhikode, India.
N P AkashDepartment of Microbiology, Government Medical College, Kozhikode, India.
T V VimishaDepartment of Microbiology, Government Medical College, Kozhikode, India.
K V KeerthiDepartment of Microbiology, Government Medical College, Kozhikode, India.
ICMR-National Institute of Virology · INGovernment Medical College · INIndian Council of Medical Research · INGovernment College Kodanchery · INGovernment of Kerala · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report here a Nipah virus (NiV) outbreak in Kozhikode district of Kerala state, India, which had caused fatal encephalitis in a 12-year-old boy and the outbreak response, which led to the successful containment of the disease and the related investigations. Quantitative real-time reverse transcription (RT)-PCR, ELISA-based antibody detection, and whole genome sequencing (WGS) were performed to confirm the NiV infection. Contacts of the index case were traced and isolated based on risk categorization. Bats from the areas near the epicenter of the outbreak were sampled for throat swabs, rectal swabs, and blood samples for NiV screening by real-time RT-PCR and anti-NiV bat immunoglobulin G (IgG) ELISA. A plaque reduction neutralization test was performed for the detection of neutralizing antibodies. Nipah viral RNA could be detected from blood, bronchial wash, endotracheal (ET) secretion, and cerebrospinal fluid (CSF) and anti-NiV immunoglobulin M (IgM) antibodies from the serum sample of the index case. Rapid establishment of an onsite NiV diagnostic facility and contact tracing helped in quick containment of the outbreak. NiV sequences retrieved from the clinical specimen of the index case formed a sub-cluster with the earlier reported Nipah I genotype sequences from India with more than 95% similarity. Anti-NiV IgG positivity could be detected in 21% of

Indexed as

COVID-19Nipah VirusChildDisease OutbreaksHumansMalePandemicsSARS-CoV-2batsKeralaNipah virus (NiV)Pteropus mediusseropositivity

Identifiers

PMID35252095
PMCPMC8891450
OpenAlexW4221014646

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.