Evidence map›Paper›PMID 35252022›Full record

ArticleFrontiers in cellular and infection microbiology2022

Differences in the Gut Microbiota Composition and Metabolites Associated With Feeding Intolerance in VLBW Infants With a Gestational Age of ≤ 30 Weeks: A Pilot Study.

Xiao-Chen Liu, Qian Sun, Yan-Chun Ji, Li-Zhen Fu, Zheng-Li Wang, Yu He, Lu-Quan Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Observational
  5. Article
  6. Succinate aggravates intestinal injury in mice with necrotizing enterocolitis.Frontiers in cellular and infection microbiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xiao-Chen LiuNeonatal Diagnosis and Treatment Centre of Children's Hospital of Chongqing Medical University, Chongqing, China.
Qian SunNeonatal Diagnosis and Treatment Centre of Children's Hospital of Chongqing Medical University, Chongqing, China.
Yan-Chun JiNeonatal Diagnosis and Treatment Centre of Children's Hospital of Chongqing Medical University, Chongqing, China.
Li-Zhen FuNeonatal Diagnosis and Treatment Centre of Children's Hospital of Chongqing Medical University, Chongqing, China.
Zheng-Li WangNeonatal Diagnosis and Treatment Centre of Children's Hospital of Chongqing Medical University, Chongqing, China.
Yu HeNeonatal Diagnosis and Treatment Centre of Children's Hospital of Chongqing Medical University, Chongqing, China.
Lu-Quan LiNeonatal Diagnosis and Treatment Centre of Children's Hospital of Chongqing Medical University, Chongqing, China.
China International Science and Technology Cooperation · CNChildren's Hospital of Chongqing Medical University · CNChongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the main variations in gut microbiota compositions, short-chain fatty acids (SCFAs) concentrations and autoinducer-2 (AI-2) levels in very-low-birth-weight (VLBW) infants with feeding intolerance (FI).

methodsTwenty-seven VLBW infants with gestational ages of ≤30 weeks were divided into the FI group (n=14) and feeding tolerance (FT) group (n=13). The gut microbiota composition and SCFAs concentrations and AI-2 levels in feces were detected at 2 and 4 weeks after birth.

resultsThere was no difference in alpha diversity between the two groups at 2 and 4 weeks after birth (

conclusionsThe main composition of the microbiota was not obviously different in infants with FI. Some SCFAs and AI-2 have moderate value in predicting FI.

Indexed as

Gastrointestinal MicrobiomeFecesGestational AgeHumansInfantInfant, NewbornInfant, Very Low Birth WeightPilot ProjectsRNA, Ribosomal, 16SRNA, Ribosomal, 16Sautoinducer-2 (AI-2)feeding intolerancegut microbiotametabolitesshort-chain fatty acids (SCFAs)

Identifiers

PMID35252022
PMCPMC8891543
OpenAlexW4213241845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.