Evidence map›Paper›PMID 35251991›Full record

ArticleFrontiers in oncology2022

Emerik Osterlund, Ari Ristimäki, Soili Kytölä, Teijo Kuopio, Eetu Heervä, Timo Muhonen, Päivi Halonen, Raija Kallio, Leena-Maija Soveri, Jari Sundström and 13 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Reclassification ofTherapeutic advances in medical oncology · 2024
    Article
  11. Article
  12. Translational gastroenterology and hepatology · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Therapeutic landscape and future direction of metastatic colorectal cancer.Nature reviews. Gastroenterology & hepatology · 2023
    Review
  17. Diagnostics (Basel, Switzerland) · 2023
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 13 institutions in 4 countries.

Emerik OsterlundDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Ari RistimäkiDepartment of Pathology, HUSLAB, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.
Soili KytöläDepartment of Genetics, HUSLAB, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.
Teijo KuopioDepartment of Pathology, Central Finland Hospital Nova, Jyväskylä, Finland.
Eetu HeerväDepartment of Oncology, Turku University Hospital, Turku, Finland.
Timo MuhonenDepartment of Oncology, South Carelia Central Hospital, Lappeenranta, Finland.
Päivi HalonenDepartment of Oncology, University of Helsinki, Helsinki, Finland.
Raija KallioDepartment of Oncology, Oulu University Hospital, Oulu, Finland.
Leena-Maija SoveriDepartment of Oncology, Helsinki University Hospital, Helsinki, Finland.
Jari SundströmDepartment of Pathology, Turku University Hospital, Turku, Finland.
Mauri KeinänenDepartment of Genetics, Fimlab Laboratories, Tampere, Finland.
Annika ÅlgarsDepartment of Oncology, Turku University Hospital, Turku, Finland.
Raija RistamäkiDepartment of Oncology, Turku University Hospital, Turku, Finland.
Halfdan SorbyeDepartment of Oncology, Haukeland University Hospital, Bergen, Norway.
Per PfeifferDepartment of Oncology, Odense University Hospital, Odense, Denmark.
Luís NunesDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Tapio SalminenDepartment of Oncology, Tampere University Hospital, Tampere, Finland.
Annamarja LamminmäkiDepartment of Oncology, Kuopio University Hospital, Kuopio, Finland.
Markus J MäkinenDepartment of Pathology, Oulu University Hospital, Oulu, Finland.
Tobias SjöblomDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Helena IsoniemiDepartment of Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland.
Bengt GlimeliusDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Pia OsterlundDepartment of Oncology, University of Helsinki, Helsinki, Finland.
University of Helsinki · FIUppsala University · SETurku University Hospital · FIHelsinki University Hospital · FIFimlab (Finland) · FIHaukeland University Hospital · NOOdense University Hospital · DKOulu University Hospital · FITampere University · FIUniversity of Eastern Finland · FIUniversity of Jyväskylä · FIUniversity of Oulu · FIUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsPatients from three Nordic population-based cohorts and the real-life RAXO-study were combined.

resultsThe

conclusionsIn these real-life and population-based cohorts, there were no significant differences in patient characteristics and outcomes between patients with

Indexed as

colorectal cancerKRAS-G12C mutationKRAS mutationmetastaticpopulation-basedreal-world

Identifiers

PMID35251991
PMCPMC8889930
OpenAlexW4212836433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.