Evidence map›Paper›PMID 35251910›Full record

ReviewPreventive medicine reports2022

Cost and effectiveness of HPV vaccine delivery strategies: A systematic review.

Alvine M Akumbom, Jennifer J Lee, Nancy R Reynolds, Winter Thayer, Jinglu Wang, Eric Slade

Abstract readReview
In one paragraph

Review in Preventive medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  7. Article
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  9. Article
  10. [Potential and limitations of school vaccination programs to increase HPV vaccination rates in Germany].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025
    Review
  11. Article
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  18. Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alvine M AkumbomJohns Hopkins University School of Nursing, 525 N. Wolfe St, Baltimore, MD 21205, USA.
Jennifer J LeeJohns Hopkins University School of Nursing, 525 N. Wolfe St, Baltimore, MD 21205, USA.
Nancy R ReynoldsJohns Hopkins University School of Nursing, 525 N. Wolfe St, Baltimore, MD 21205, USA.
Winter ThayerJohns Hopkins University School of Nursing, 525 N. Wolfe St, Baltimore, MD 21205, USA.
Jinglu WangStanford Medicine, 1840 Embarcadero Road, Palo Alto, CA 9430, USA.
Eric SladeJohns Hopkins University School of Nursing, 525 N. Wolfe St, Baltimore, MD 21205, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fifteen years following the approval of the first human papillomavirus (HPV) vaccine, cervical cancer continues to be a significant source of morbidity and mortality among women in low-resource settings. It is the second-leading cause of cancer-related deaths in women globally and the leading cause of cancer-related deaths in Sub-Saharan Africa. Vaccine delivery and programmatic costs may hinder the distribution of HPV vaccines in low-resource settings, and ultimately influence access to HPV vaccines. While reviews have been conducted on the cost-effectiveness of HPV vaccines, little is known about the cost and effectiveness of vaccination strategies. The purpose of this systematic review was to synthesize evidence on the cost and cost-effectiveness of vaccination strategies utilized to increase access to HPV vaccines. Search queries were created for CINAHL Plus, Embase, and PubMed. Our search strategy focused on articles that contained information on HPV vaccine uptake/reach, HPV vaccination costs, or the cost-effectiveness of HPV vaccination programs. We retrieved 773 articles from the databases, assessed 251 full-texts, and included 15 articles in our final synthesis. Countries without national HPV vaccination programs aimed to identify and adopt sustainable strategies to make HPV vaccines available to adolescents through demonstration programs. In contrast, countries with national vaccination programs focused on identifying cost-effective interventions to increase vaccination rates to meet nationally recommended standards. There is a dire need for HPV vaccination programs and intervention studies tailored to settings in low- and middle-income countries to increase access to HPV vaccines. Future studies should also evaluate the cost-effectiveness of implemented strategies.

Indexed as

AccessCostDelivery strategyEffectiveness or reachHuman papillomavirus or HPVVaccine

Identifiers

PMID35251910
PMCPMC8889236

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.