Evidence map›Paper›PMID 35251741›Full record

ArticleWestern Pacific surveillance and response journal : WPSAR

Re-positive testing, clinical evolution and clearance of infection: results from COVID-19 cases in isolation in Viet Nam.

Ngoc-Anh Hoang, Thai Quang Pham, Ha-Linh Quach, Khanh Cong Nguyen, Samantha Colquhoun, Stephen Lambert, Duong Huy Luong, Quang Dai Tran, Dinh Cong Phung, Tran Nhu Duong and 5 more

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Article in Western Pacific surveillance and response journal : WPSAR. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Ngoc-Anh HoangDepartment of Epidemiology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.
Thai Quang PhamDepartment of Epidemiology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.
Ha-Linh QuachDepartment of Epidemiology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.
Khanh Cong NguyenDepartment of Epidemiology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.
Samantha ColquhounNational Centre for Epidemiology and Population Health, Research School of Population Health, College of Health and Medicine, Australian National University, Canberra, Australia.
Stephen LambertNational Centre for Epidemiology and Population Health, Research School of Population Health, College of Health and Medicine, Australian National University, Canberra, Australia.
Duong Huy LuongDepartment of Epidemiology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.
Quang Dai TranGeneral Department of Preventive Medicine, Ministry of Health, Hanoi, Viet Nam.
Dinh Cong PhungNational Agency for Science and Technology Information, Ministry of Science and Technology, Viet Nam.
Tran Nhu DuongNational Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.
Nghia Duy NguDepartment of Epidemiology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.
Tu Anh TranDepartment of Epidemiology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.
Hue Bich Thi NguyenNational Hospital of Tropical Diseases, Hanoi, Viet Nam.
Duc-Anh DangNational Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.
Florian VogtNational Centre for Epidemiology and Population Health, Research School of Population Health, College of Health and Medicine, Australian National University, Canberra, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAsymptomatic infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and test re-positivity after a negative test have raised concerns about the ability to effectively control the coronavirus disease 2019 (COVID-19) pandemic. We aimed to investigate the prevalence of COVID-19 asymptomatic and pre-symptomatic infections during the second wave of COVID-19 in Viet Nam, and to better understand the duration of SARS-CoV-2 infection and the dynamics between the evolution of clinical symptoms and SARS-CoV-2 test positivity among confirmed COVID-19 cases.

methodsWe conducted a cohort analysis on the first 50 confirmed cases during the second COVID-19 wave in Viet Nam using clinical, laboratory and epidemiological data collected from 9 March to 30 April 2020. Kaplan-Meier estimates were used to assess time to clearance of SARS-CoV-2 infection, and log-rank tests were used to explore factors related to time to SARS-CoV-2 infection clearance.

resultsMost cases (58%) had no typical signs or symptoms of COVID-19 at the time of diagnosis. Ten cases (20%) were re-positive for SARS-CoV-2 during infection. Eight cases (16%) experienced COVID-19 symptoms after testing negative for SARS-CoV-2. The median duration from symptom onset until clearance of infection was 14 days (range: 6-31); it was longer in re-positive and older patients and those with pre-existing conditions.

conclusionAsymptomatic and pre-symptomatic infections were common during the second wave of COVID-19 in Viet Nam. Re-positivity was frequent during hospitalization and led to a long duration of SARS-CoV-2 infection.

Indexed as

COVID-19HospitalizationHumansPandemicsSARS-CoV-2Vietnam

Identifiers

PMID35251741
PMCPMC8873913

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.