Evidence map›Paper›PMID 35251712›Full record

ArticleAIDS research and treatment2022

A Retrospective Study of Incidence and Predictors on Mother-to-Child Transmission of HIV among HIV-Exposed Infants in West Guji Zone, Southern Ethiopia.

Girish Degavi, Boko Loka Safayi, Shiferaw Gelchu Adola, Biniyam Demisse, Takala Utura, Udessa Gemeda, Sarah Ezhil Kelna Edwin, Fitsum Demissie

Open access · goldAbstract read
In one paragraph

Article in AIDS research and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Girish DegaviSchool of Nursing and Midwifery, Institute of Health, Bule Hora University, Hageremaryam, Ethiopia.ORCID https://orcid.org/0000-0002-0852-6344
Boko Loka SafayiSchool of Nursing and Midwifery, Institute of Health, Bule Hora University, Hageremaryam, Ethiopia.
Shiferaw Gelchu AdolaSchool of Nursing and Midwifery, Institute of Health, Bule Hora University, Hageremaryam, Ethiopia.
Biniyam DemisseSchool of Nursing, College of Medicine and Health Science, Arbaminch University, Arbaminch, Ethiopia.
Takala UturaSchool of Public Health, Institute of Health, Bule Hora University, Hageremaryam, Ethiopia.
Udessa GemedaSchool of Nursing and Midwifery, Institute of Health, Bule Hora University, Hageremaryam, Ethiopia.
Sarah Ezhil Kelna EdwinSchool of Nursing and Midwifery, Institute of Health, Bule Hora University, Hageremaryam, Ethiopia.ORCID https://orcid.org/0000-0002-4657-956X
Fitsum DemissieDepartment of Pharmacy, Institute of Health, Bule Hora University, Hageremaryam, Ethiopia.
Bule Hora University · ETArba Minch University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe transmission of HIV from mother to child among HIV-positive infants is estimated to be higher than 20%, despite the fact that antiretroviral treatment is available for antenatal mothers with HIV. In Ethiopia, the prevalence of HIV transmission from mother to child among infants aged one and a half years is estimated to be approximately 15.7 percent.

methodsA retrospective cohort analysis using a simple random sampling technique was incorporated among 422 HIV-exposed babies and their mothers who were randomly chosen and screened using OPD (outpatient card) from March 2019 to March 2021 in the general hospitals of West Guji zone, Oromia, Ethiopia. The data were coded and entered into EpiData version 4.6.1 and exported to SPSS version 23 for cleaning and analysis.

resultThe study revealed that at the end of follow-up, 3.8% of the HIV-exposed infants were found to be HIV positive. Poor adherence of infant for CPT (AOR: 5.6; 95% CI: 1.010-27.24), father not enrolled to ART (AOR: 4.4; 95% CI: 1.187-15.724), age of infants at enrollment >6 weeks (AOR: 4.5; 95% CI: 1.102-16.1), mother's enrollment to PMTCT during labor and delivery or after (AOR: 6.84; 95% CI: 1.316-42.743), and mothers on the WHO clinical stage mild or advanced (AOR: 3.6; 95% CI: 1.146-16.842) was found to be the most important significant predictors of mother-to-child transmission of HIV.

conclusionSeveral factors included in the study were the main predictors of mother-to-child transmission of HIV. The study concluded that there are some lacunae in the prevention of MTCT of HIV but that the incidence of MTCT of HIV was significantly lower in this part of the world.

Identifiers

PMID35251712
PMCPMC8890858
OpenAlexW4213432941

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.