ArticleSAGE open medicine2022
Severe Acute Malnutrition (SAM) associated mortality rate of children attending HIV/AIDS care in North West Ethiopia, 2009-2019.
Article in SAGE open medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- Risk and Protective Factors Associated With HIV-Related Mortality in Children Receiving Antiretroviral Therapy: A Model-Based Meta-Regression.JAMA pediatrics · 2026Pooled it
- Incidence and predictors of common opportunistic infections among children less than 15 years of age on antiretroviral therapy in Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Article
- Incidence and Risk Factors of Mortality Among Under Five Children with Severe Acute Malnutrition Admitted at Hoima Regional Referral Hospital in Uganda.Pediatric health, medicine and therapeutics · 2026Article
- Management challenges of supplementary feeding programs for severe acute malnutrition among children under five years: a qualitative study in Ethiopia.Discover social science and health · 2025Article
- Prevalence and related factors of TB/HIV co-infection among hospitalized children with tuberculosis in Southwest China.Frontiers in cellular and infection microbiology · 2025Article
- Survival status and its predictors among undernourished children on antiretroviral therapy in Bahir Dar city, Northwest Ethiopia, 2010 - 2020, a multicenter retrospective cohort study.BMC pediatrics · 2024Article
- Trends Analysis of HIV Infection and Antiretroviral Treatment Outcome in Amhara Regional from 2015 to 2021, Northeast Ethiopia.HIV/AIDS (Auckland, N.Z.) · 2023Article
- Rate, risk factors and estimations of time to develop severe acute malnutrition after children receiving antiretroviral therapy at selected health facilities in northwest Ethiopia.Journal of nutritional science · 2023Article
- Incidence and predictors of attrition rate after children started inpatient treatments for complicated severe acute malnutrition in North West Ethiopia.Journal of health, population, and nutrition · 2022Article
- Malaria serosurvey among acute febrile patients come for health care seeking at the high malaria-endemic setting of North West Ethiopia.SAGE open medicine · 2022Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to assess Severe Acute Malnutrition (SAM) associated mortality rate of children attending HIV/AIDS care in North West Ethiopia 2009-2019.
methodsInstitutional-based retrospective cohort study was employed among 721 on antiretroviral therapy care seropositive children since 2009-2019. Data were entered using EpiData version 4.2 and exported to STATA (SE) R-14 version statistical software for further analysis. Beside, Besides, WHO (World Health Organization) Anthro Plus software was used to assess the nutritional status of the children. Bivariable and multivariable Cox regression analyses were conducted to identify the predictors of mortality. Finally, variables with p-value less than 0.05 were considered significant predictors of mortality.
resultOverall, 721 (N = 721) seropositive children were included with a mean (±SD) age of 118.4 ± 38.24 months. A median time of death was reported at 19.5 months (interquartile range = ±8.5). The overall mortality rate in this study was determined as 5.4 per 100 child-years (95% confidence interval: 3.6-5.8). Severe stunting (height for age Z-score <-3) (hazard ratio = 2.9, 95% confidence interval: 1.8-6.4), admission with septic shock (hazard ratio = 2.3, 95% confidence interval: 1.2-4.3, p < 0.008), CD4+ count below threshold (hazard ratio = 1.6, 95% confidence interval: 1.19-7.9), and World Health Organization Stages III and IV (hazard ratio = 2.9, 95% confidence interval: 1.8-6.4) were at high risk of mortality.
conclusionA high rate of SAM associated mortality rate within short median (±SD) time to death was reported as compared with previous finding in Ethiopia. Seropositive children presenting with CD4 counts being below a threshold, World Health Organization Stages III and IV, and being nutritionally stunted during antiretroviral therapy initiation were at high risk of early mortality.
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