Evidence map›Paper›PMID 35251634›Full record

ArticleMolecular and clinical oncology2022

Effects of endoplasmic reticulum stress-mediated CREB3L1 on apoptosis of glioma cells.

Zhao Yan, Yaxin Hu, Yiwei Zhang, Qian Pu, Liangzhao Chu, Jian Liu

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhao YanDepartment of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China.
Yaxin HuDepartment of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China.
Yiwei ZhangDepartment of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China.
Qian PuDepartment of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China.
Liangzhao ChuDepartment of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China.
Jian LiuDepartment of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China.
Guiyang Medical University · CNAffiliated Hospital of Guizhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between endoplasmic reticulum stress (ERS) and apoptosis has been extensively studied. Cyclic adenosine monophosphate responsive element binding protein 3 like 1 (CREB3L1) has an important role in the development of glioma. In the present study, the potential association between ERS-induced apoptosis and CREB3L1 and its clinical implications were investigated. From a total of 30 cases, brain gliomas with different pathological grades surgically resected at the Department of Neurosurgery of the Affiliated Hospital of Guizhou Medical University (Guiyang, China) between January 2018 and January 2019 were collected. The expression of CREB3L1 and ERS-related proteins in gliomas with different degrees of malignancy was detected by immunohistochemistry. Furthermore, U87-MG glioma cells were cultured

Indexed as

apoptosisCREB3L1endoplasmic reticulum stressglioma cellsthapsigarginU87-MG

Identifiers

PMID35251634
PMCPMC8892456
OpenAlexW4212764812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.