Evidence map›Paper›PMID 35251631›Full record

ArticleMolecular and clinical oncology2022

Association between fatty acid synthase and adipophilin expression in triple-negative breast cancer.

Katsuhiro Yoshikawa, Mitsuaki Ishida, Hirotsugu Yanai, Koji Tsuta, Mitsugu Sekimoto, Tomoharu Sugie

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Katsuhiro YoshikawaDepartment of Pathology and Division of Diagnostic Pathology, Kansai Medical University, Hirakata, Osaka 573-1191, Japan.
Mitsuaki IshidaDepartment of Pathology and Division of Diagnostic Pathology, Kansai Medical University, Hirakata, Osaka 573-1191, Japan.
Hirotsugu YanaiDepartment of Pathology and Division of Diagnostic Pathology, Kansai Medical University, Hirakata, Osaka 573-1191, Japan.
Koji TsutaDepartment of Pathology and Division of Diagnostic Pathology, Kansai Medical University, Hirakata, Osaka 573-1191, Japan.
Mitsugu SekimotoDepartment of Surgery, Kansai Medical University, Hirakata, Osaka 573-1191, Japan.
Tomoharu SugieDepartment of Surgery, Kansai Medical University, Hirakata, Osaka 573-1191, Japan.
Kansai Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is well known that cancer cells produce energy via anaerobic glycolysis. Lipid metabolism is often upregulated in numerous types of cancer. Our previous study demonstrated that adipophilin (ADP), a lipid-associated protein, was a poor prognostic indicator in patients with triple-negative breast cancer (TNBC). However, the mechanism of ADP expression in TNBC remains unclear. Fatty acid synthase (FASN) is a crucial enzyme in

Indexed as

adipophilinfatty acid synthaselipid metabolismtriple-negative breast cancer

Identifiers

PMID35251631
PMCPMC8892429
OpenAlexW4210868349

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.