ArticleClinics in orthopedic surgery2022
Sex Differences in Serum C-Reactive Protein Course after Total Hip Arthroplasty.
Article in Clinics in orthopedic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Gender equality challenges in orthopaedic surgery: a systematic review.International orthopaedics · 2023Pooled it
- Machine learning analysis identifies key predictors of baseline lung allograft dysfunction and increased mortality in lung transplant patients.JHLT open · 2026Article
- Factors Affecting the Elevation of Inflammatory Markers Before Primary Total Hip Arthroplasty.Arthroplasty today · 2025Article
- Postoperative Patient-Reported Pain and Opioid Consumption After Total Hip Arthroplasty: A Propensity Score-Matched Comparison of the Direct Superior and Posterior Approaches.Journal of clinical medicine · 2025Article
- The influencing factors of postoperative sleep disorders in elderly patients undergoing hip replacement surgery under general anesthesia and the construction and validation of a nomogram prediction model.Frontiers in neurology · 2025Article
- Elastic Compression Dressing after Total Hip Replacement Slightly Reduces Leg Swelling: A Randomized Controlled Trial.Journal of clinical medicine · 2024Article
- Dynamics of C-reactive protein level after orthopedic surgeries.Journal of orthopaedics · 2024Article
- Sex differences in inflammatory parameters after shoulder arthroplasty and blood loss.Frontiers in surgery · 2024Article
- C-reactive protein during the first 6 postoperative days after total hip arthroplasty cannot predict early periprosthetic infection.Archives of orthopaedic and trauma surgery · 2023Article
- Do Elevated Serum C-Reactive-Protein Levels Excuse Delayed Surgery for Femoral Neck Fractures?Antibiotics (Basel, Switzerland) · 2023Article
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6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundGender-specific medicine has become an important part in investigating the course of various diseases. C-reactive protein (CRP) is used as an inflammatory marker for detecting inflammations and even infections after total hip arthroplasty (THA). The general course of CRP after THA is well known, but there is controversy about its association with sex. Therefore, we aimed to investigate if there is an influence of sex on the CRP after THA in the first 10 days after operation in a complication-free course in male and female patients and to re-evaluate the specific postoperative CRP course with its maximum on the second to third postoperative days.
methodsWe retrospectively reviewed patients who had been treated with THA due to primary osteoarthritis through the same approach using an equal model of a cementless stem and a cup and complication-free between 2013 and 2016. Patients with active inflammation, rheumatoid arthritis, secondary arthrosis, active cancer disease, and documented postoperative complications were not included. The CRP values before THA and up to 10 days after THA were recorded and tested for sex discrepancy. Factor analyses were performed, and CRP values were adjusted for confounders (age, operation time, diabetes mellitus, and body mass index [BMI]).
resultsA total of 1,255 patients (728 women and 527 men) were finally analyzed. Men were younger and had a longer operation time and a higher BMI compared to women. The prevalence of overweight was higher in men, while obesity (BMI > 40 kg/m
conclusionsBased on the results of more precise sex-specific evaluation of the postoperative CRP course after THA, the present study showed for the first time that there was a gender discrepancy in the CRP course after complication-free THA in the first 7 postoperative days. Furthermore, this study confirmed the postoperative CRP course with its maximum on the third postoperative day.
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