Evidence map›Paper›PMID 35251468›Full record

ArticleOxidative medicine and cellular longevity2022

The Current Status of Antioxidants in the Treatment of Vitiligo in China.

Ying Zhou, Manal Khan, Ling Jiang, Chuhan Fu, Yumeng Dong, Liping Luo, Haoran Guo, Lijuan Gao, Xinxin Lei, Li Zhang and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Ying ZhouDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Manal KhanDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Ling JiangDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Chuhan FuDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Yumeng DongDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Liping LuoDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Haoran GuoDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Lijuan GaoDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Xinxin LeiDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Li ZhangDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Xing YuDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Li LeiDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Jinhua HuangDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Jing ChenDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Qinghai ZengDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0003-2140-543X
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Little is known about the use of antioxidants in the clinical treatment of vitiligo. To investigate the specific use of antioxidants in the treatment of vitiligo and the possible reasons behind its use in China, we conducted a prospective questionnaire-based study using an online questionnaire comprising 26 questions in 5 areas. A total of 323 clinical frontline dermatologists participated in this study. Differences among groups were compared using Pearson's chi-square test. Ordinal logistic regression was used to develop knowledge-use multiple regression models. Among the 323 dermatologists, 293 (90.7%) approved the oxidative stress theory of vitiligo, and 182 (56.3%) encouraged the use of antioxidants for treating vitiligo; nonetheless, only 11.8% frequently treated vitiligo with antioxidants. Insufficient knowledge of antioxidants was a significant predictor of lower frequency of antioxidant usage (adjusted odds ratio, 0.401 [95% confidence interval, 0.256-0.629];

Indexed as

Health Knowledge, Attitudes, PracticeAdministration, OralAdministration, TopicalAdultAntioxidantsChinaChi-Square DistributionDermatologistsFemaleHumansLogistic ModelsMaleMiddle AgedOxidative StressProspective StudiesSurveys and QuestionnairesAntioxidants

Identifiers

PMID35251468
PMCPMC8896159
OpenAlexW4214490408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.