Evidence map›Paper›PMID 35251423›Full record

ArticleRadiology case reports2022

Severe hypercalcemia complicated by acute pancreatitis revealing generalized bone lysis metastasis: Case report and review.

Nour El Houda Lamassab, Meryem Jabri, Hajar Benzekri, Youness Dendane, Chaimae Daoudi, Fadoua Jebrouni, Abderrahim Lachhab, Mourad Hmidouch, Mohammed Baddi, Siham Nasri and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Radiology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Diagnostic and therapeutic management of severe acute pancreatitis. Evidence based medicine (EBM) clinical practice guidelines.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Nour El Houda LamassabFaculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Meryem JabriFaculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Hajar BenzekriFaculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Youness DendaneFaculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Chaimae DaoudiFaculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Fadoua JebrouniFaculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Abderrahim LachhabFaculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Mourad HmidouchFaculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Mohammed BaddiFaculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Siham NasriFaculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Skiker ImaneFaculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Noureddine OulaliFaculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Mohamed I University · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant hypercalcemia is a frequent metabolic complication of osteophilic tumors, exceptionally revealing cavitary cancer, but its prognosis remains poor despite early and adequate management. We report the case of a young patient, smoker without any previous history, admitted for the management of a digestive symptoms made of abdominal pain with food vomiting. The patient had an electrocardiogram withchest computed tomography scan and BBC evoking PA on malignant hypercalcemia. An etiological investigation was conducted to confirm the tumoral origin of the hypercalcemia. We put the patient on hyperhydration with corticotherapie and biohosphonates with a good clinical and biological improvement. Malignant hypercalcemia affects about 10%-20% of patients with cancer including nasopharyngeal carcinoma. Its clinical presentation varies according to the extent and speed of onset, responsible for multivisceral involvement including kidney, heart, neuropsychiatric system, which may engage the patient's vital prognosis. The therapeutic management is based on 4 main principles; hyperhydration, increase of urinary calcium excretion by loop diuretics, decrease of bone resorption by biphosphonates and extrarenal purification which remains the ideal choice in case of life-threatening severe hypercalcemia. Acute hypercalcemic pancreatitis as a mode of revelation of cavum cancer has almost never been described in the literature.

Indexed as

Acute pancreatitsHypercalcemiaMalignacyNasopharyngea neoplasie

Identifiers

PMID35251423
PMCPMC8892014
OpenAlexW4214813654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.