Evidence map›Paper›PMID 35251392›Full record

ArticleWideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques2022

Role of magnetic resonance-high intensity focused ultrasound (MR-HIFU) in uterine fibroids management: an updated systematic review and meta-analysis.

Shilin Zheng, Yu Rong, Haiyun Zhu, Xiaoyu Zhang, Xuan Liu, Yun Wu, Meng Zhao

Open access · goldAbstract read
In one paragraph

Article in Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Shilin ZhengDepartment of Interventional Medicine Ward, Wuhan Third Hospital-Tongren Hospital of Wuhan University, Wuhan, China.
Yu RongDepartment of Radiology, Guizhou Provincial People's Hospital, Guizhou Provincial Key Laboratory of Intelligent Medical Image Analysis and Precision Diagnosis, Guizhou Provincial People's Hospital, Guiyang, Guizhou, China.
Haiyun ZhuDepartment of Imaging section, Linyi County People's Hospital, Dezhou City, Shandong Province, Shandong Dezhou Linyi, China.
Xiaoyu ZhangDepartment of Radiology, Affiliated Hospital of Chifeng University, Chifeng, China.
Xuan LiuDepartment of Interventional Medicine Ward, Wuhan Third Hospital-Tongren Hospital of Wuhan University, Wuhan, China.
Yun WuDepartment of Interventional Medicine Ward, Wuhan Third Hospital-Tongren Hospital of Wuhan University, Wuhan, China.
Meng ZhaoDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Tongren Hospital · CNChifeng University · CNGuizhou Provincial People's Hospital · CNJiangsu Province Hospital · CNLinyi People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMagnetic resonance-high intensity focused ultrasound (MR-HIFU) has revolutionized the treatment of Uterine fibroids. Usually, they are associated with prolonged heavy bleeding during the menstrual period, sacral pain, and increased frequency of UTIs, secondary dysmenorrhea, constipation, and pregnancy-associated problems. It also impacts usual activities, which lead to diminished quality of life and rising healthcare costs. Generally, surgery is the only choice for uterine fibroids; however, MR-HIFU is an entirely non-invasive novel therapy, preferred in pregnancy desiring females.

aimTo re-evaluate the efficacy of magnetic resonance-high intensity focused ultrasound (MRHIFU) therapy for uterine fibroids. MATERIAL AND

methodsRandomized clinical trials (RCTs), prospective or retrospective non-randomized, and cross-over studies that considered clinically symptomatic uterine fibroid treatment were included. Meta-analysis was performed using NCSS software, and data were analyzed at a 95% confidence level with a significance level of 0.05. In addition, the non-perfused volume percentage (NPV%), transformed Symptom Severity Score percentage change (tSSS change%), and health-related quality of life (HR-QoL) were computed.

resultsThe overall effect of NPV% was 67.60%, where the 95% confidence interval ranged from 55.58% to 79.62%. The overall impact of tSSS% change was approximately 50% (0.54) with 95% CI of 0.41-0.66 of 3 months, 6 months, and 12 months in the included studies. There was a significant improvement in the health-related quality of life (HR-QoL).

conclusionsThe efficacy of MR-HIFU therapy was improved as treatment protocols aimed for total ablation.

Indexed as

health-related quality of life (HRQoL)magnetic resonance-high intensity focused ultrasound (MR-HIFU)meta-analysisuterine artery embolization (UAE)uterine fibroids

Identifiers

PMID35251392
PMCPMC8886476
OpenAlexW3205988569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.