Evidence map›Paper›PMID 35251368›Full record

ReviewBehavioural neurology2022

An Updated Overview of the Magnetic Resonance Imaging of Brain Iron in Movement Disorders.

Nicola Tambasco, Pasquale Nigro, Andrea Chiappiniello, Federico Paolini Paoletti, Sara Scialpi, Simone Simoni, Pietro Chiarini, Lucilla Parnetti

Open access · goldAbstract readReview
In one paragraph

Review in Behavioural neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. 7T MRI detects widespread brain iron deposition in neuroferritinopathy.Annals of clinical and translational neurology · 2024
    Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nicola TambascoMovement Disorders Center, Neurology Department, Perugia General Hospital and University of Perugia, Perugia, Italy.ORCID https://orcid.org/0000-0003-1497-4482
Pasquale NigroMovement Disorders Center, Neurology Department, Perugia General Hospital and University of Perugia, Perugia, Italy.ORCID https://orcid.org/0000-0002-2736-0095
Andrea ChiappinielloDepartment of Medical Physics, Perugia General Hospital, Perugia, Italy.ORCID https://orcid.org/0000-0002-7135-985X
Federico Paolini PaolettiMovement Disorders Center, Neurology Department, Perugia General Hospital and University of Perugia, Perugia, Italy.
Sara ScialpiMovement Disorders Center, Neurology Department, Perugia General Hospital and University of Perugia, Perugia, Italy.
Simone SimoniMovement Disorders Center, Neurology Department, Perugia General Hospital and University of Perugia, Perugia, Italy.ORCID https://orcid.org/0000-0003-3715-660X
Pietro ChiariniNeuroradiological Unit, Perugia General Hospital, Perugia, Italy.
Lucilla ParnettiNeurology Department, Perugia General Hospital and University of Perugia, Perugia, Italy.ORCID https://orcid.org/0000-0001-5722-3967
University of Perugia · ITAzienda Ospedaliera di Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain iron load is one of the most important neuropathological hallmarks in movement disorders. Specifically, the iron provides most of the paramagnetic metal signals in the brain and its accumulation seems to play a key role, although not completely explained, in the degeneration of the basal ganglia, as well as other brain structures. Moreover, iron distribution patterns have been implicated in depicting different movement disorders. This work reviewed current literature on Magnetic Resonance Imaging for Brain Iron Detection and Quantification (MRI-BIDQ) in neurodegenerative processes underlying movement disorders.

Indexed as

IronMovement DisordersBrainHumansMagnetic Resonance ImagingNeuroimagingIron

Identifiers

PMID35251368
PMCPMC8894064
OpenAlexW4214747130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.