Evidence map›Paper›PMID 35250908›Full record

ArticleFrontiers in microbiology2021

Incorporating Within-Host Diversity in Phylogenetic Analyses for Detecting Clusters of New HIV Diagnoses.

August Guang, Mark Howison, Lauren Ledingham, Matthew D'Antuono, Philip A Chan, Charles Lawrence, Casey W Dunn, Rami Kantor

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

August GuangCenter for Computational Biology of Human Disease, Brown University, Providence, RI, United States.
Mark HowisonResearch Improving People's Lives, Providence, RI, United States.
Lauren LedinghamDivision of Infectious Diseases, The Alpert Medical School, Brown University, Providence, RI, United States.
Matthew D'AntuonoDivision of Infectious Diseases, The Alpert Medical School, Brown University, Providence, RI, United States.
Philip A ChanDivision of Infectious Diseases, The Alpert Medical School, Brown University, Providence, RI, United States.
Charles LawrenceDivision of Applied Mathematics, Brown University, Providence, RI, United States.
Casey W DunnDepartment of Ecology and Evolutionary Biology, Yale University, New Haven, CT, United States.
Rami KantorDivision of Infectious Diseases, The Alpert Medical School, Brown University, Providence, RI, United States.
Brown University · USYale University · US

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
NIAID NIH HHS P30 AI042853NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

backgroundPhylogenetic analyses of HIV sequences are used to detect clusters and inform public health interventions. Conventional approaches summarize within-host HIV diversity with a single consensus sequence per host of the

methodsWe introduce

resultsDISCUSSION:

Indexed as

cluster inferenceconsensus sequenceHIVnear-whole-genomenext generation sequencing (NGS)phylogeneticsprofile samplingtransmission disruption

Identifiers

PMID35250908
PMCPMC8891961
OpenAlexW4213032483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.