Evidence map›Paper›PMID 35250862›Full record

ArticleFrontiers in endocrinology2022

Assessment of Osteoporosis in Lumbar Spine:

Jin Liu, Jian-Wei Liao, Wei Li, Xiao-Jun Chen, Jia-Xin Feng, Lin Yao, Pan-Hui Huang, Zhi-Hai Su, Hai Lu, Yu-Ting Liao and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Jin LiuDepartment of Radiology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.
Jian-Wei LiaoDepartment of Radiology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.
Wei LiDepartment of Radiology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.
Xiao-Jun ChenDepartment of Radiology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.
Jia-Xin FengDepartment of Radiology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.
Lin YaoDepartment of Radiology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.
Pan-Hui HuangDepartment of Radiology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.
Zhi-Hai SuDepartment of Spinal Surgery, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.
Hai LuDepartment of Spinal Surgery, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.
Yu-Ting LiaoMR Research, GE Healthcare, Guangzhou, China.
Shao-Lin LiDepartment of Radiology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.
Ya-Jun MaDepartment of Radiology, University of California San Diego, La Jolla, CA, United States.
Sun Yat-sen University · CNFifth Affiliated Hospital of Sun Yat-sen University · CNUniversity of California, San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimBone collagen matrix makes a crucial contribution to the mechanical properties of bone by imparting tensile strength and elasticity. The collagen content of bone is accessible

methodsA total of 189 participants with a mean age of 56 (ranged from 50 to 86) years old were underwent MRI, quantitative computed tomography (QCT), and dual-energy X-ray absorptiometry (DXA) in lumbar spine. Major fracture risk was also evaluated for all participants using Fracture Risk Assessment Tool (FRAX). Lumbar CBWPD, bone marrow fat fraction (BMFF), bone mineral density (BMD) and T score values were calculated in three vertebrae (L2-L4) for each subject. Both the CBWPD and BMFF were correlated with BMD, T score, and FRAX score for comparison. The abilities of the CBWPD and BMFF to discriminate between three different cohorts, which included normal subjects, patients with osteopenia, and patients with osteoporosis, were also evaluated and compared using receiver operator characteristic (ROC) analysis.

resultsThe CBWPD showed strong correlation with standard BMD (R

conclusionThe STAIR-UTE-measured CBWPD is a promising biomarker in the assessment of bone quality and fracture risk.

Indexed as

Fractures, BoneOsteoporosisAgedAged, 80 and overCancellous BoneCollagenHumansLumbar VertebraeMagnetic Resonance ImagingMiddle AgedWaterCollagenWaterbone marrow fat fractionbone mineral densitycollagen bound water proton densityosteoporosisultrashort echo time

Identifiers

PMID35250862
PMCPMC8888676
OpenAlexW4212944011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.