ArticleFrontiers in endocrinology2021
A Nomogram to Predict Regrowth After Ultrasound-Guided Radiofrequency Ablation for Benign Thyroid Nodules.
Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Long-term clinical outcomes of thermal ablation for benign thyroid nodules and unresolved issues: a comprehensive systematic review.La Radiologia medica · 2025Pooled it
- Radiomic Analysis as a Powerful Tool for Cytological Images of Benign Thyroid Nodules Treated by Thermal Radiofrequency Ablation.Bioengineering (Basel, Switzerland) · 2026Article
- Pre-ablation derived neutrophil-to-lymphocyte ratio is associated with time to complete disappearance after thermal ablation of benign thyroid nodules: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- Comparison of two ablation methods in benign thyroid nodules: Radiofrequency ablation and non-cooled microwave ablation.Journal of clinical imaging science · 2026Article
- Radiofrequency Ablation for Thyroid Nodules (RATED Study)-Analysis of a Learning Curve and Predictors of Success.The Journal of clinical endocrinology and metabolism · 2025Observational
- Predictors of Suboptimal Response After Radiofrequency Ablation of Benign Thyroid Nodules.Journal of clinical medicine · 2025Article
- Assessing the impact of malignant thyroid nodules on the efficacy of radiofrequency ablation: a single-center prospective study.Frontiers in endocrinology · 2025Article
- A prognostic model for thermal ablation of benign thyroid nodules based on interpretable machine learning.Frontiers in endocrinology · 2024Article
- A 6-year single-center prospective follow-up study of the efficacy of radiofrequency ablation for thyroid nodules.Frontiers in endocrinology · 2024Article
- Development and validation of a nomogram model for predicting residue of partially cystic thyroid nodules after ultrasound-guided ethanol and thermal ablation.Frontiers in endocrinology · 2023Article
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5 authors.
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Abstract
objectiveTo develop and validate a nomogram to predict regrowth for patients with benign thyroid nodules undergoing radiofrequency ablation (RFA).
methodsA total of 200 patients with 220 benign thyroid nodules who underwent RFA were included in this respective study. After RFA, patients were followed up at 1, 3, 6, and 12 months, and every 12 months thereafter. Regrowth was defined as an increase in nodule volume 50% over the previously recorded smallest volume. A nomogram was developed based on the variables identified by multivariate logistic regression and the model performance was evaluated by discrimination(concordance index) and calibration curves.
resultsThe incidence of regrowth was 13.64% (30/220) after a mean follow-up period of 27.43 ± 17.99 months. Multivariate logistic regression revealed initial volume (OR = 1.047, 95%CI 1.020-1.075), vascularity (OR = 2.037, 95%CI 1.218-3.404), and location close to critical structure (OR = 4.713, 95%CI 1.817-12.223) were independent factors associated with regrowth. The prognostic nomogram incorporating these three factors achieved good calibration and discriminatory abilities with a concordance index of 0.779 (95%CI 0.686-0.872).
conclusionsA prognostic nomogram was successfully developed to predict nodule regrowth after RFA, which might guide physician in stratifying patients and provide precise guidance for individualized treatment protocols.
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