Evidence map›Paper›PMID 35250836›Full record

ArticleFrontiers in neurology2022

Gut Microbiota and Targeted Biomarkers Analysis in Patients With Cognitive Impairment.

Shourong Lu, Ying Yang, Qiao Xu, Shuqiang Wang, Jie Yu, Bingshan Zhang, Zhuo Wang, Yunyun Zhang, Wenwei Lu, Kan Hong

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Shourong LuDepartment of Geriatric, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Ying YangDepartment of Geriatric, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Qiao XuDepartment of Geriatric, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Shuqiang WangDepartment of Medicine, Wuxi Xin'an Community Health Service Center, Wuxi, China.
Jie YuDepartment of Geriatric, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Bingshan ZhangDepartment of Geriatric, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Zhuo WangDepartment of Geriatric, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Yunyun ZhangDepartment of General Practice, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Wenwei LuState Key Laboratory of Food Science and Technology and School of Food Science and Technology, Jiangnan University, Wuxi, China.
Kan HongDepartment of Geriatric, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Wuxi People's Hospital · CNNanjing Medical University · CNState Key Laboratory of Food Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbial alteration is closely associated with brain disorders including cognitive impairment (CI). Gut microbes have the potential to predicate the development of diseases. However, the gut microbial markers for CI remain to be elucidated. In this study, the gut microbial alterations were assessed using16S rRNA sequencing, and identified the gut microbial markers using a random forest model. The results showed that there were significant gut microbial differences between the control and CI groups based on beta diversity (

Indexed as

Bifidobacteriumbiomarkerscognitive impairmentgut microbiomeLactobacillus

Identifiers

PMID35250836
PMCPMC8891499
OpenAlexW4212893321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.