ArticleFrontiers in neurology2022
Age Specific Models to Capture the Change in Risk Factor Contribution by Age to Short Term Primary Ischemic Stroke Risk.
Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Prediction models for incident stroke in the community: a systematic review and meta-analysis of predictive performance.European heart journal. Digital health · 2026Article
- Mortality Trend of Cerebrovascular Disorders: A Cross-sectional Study in Northern Iran (2016-2023).Archives of Iranian medicine · 2026Article
- Proportional Stroke Mortality in Espírito Santo, Brazil: A 20-Year Joinpoint Regression Study.Epidemiologia (Basel, Switzerland) · 2025Article
- Predicting the risk of ischemic stroke in patients with atrial fibrillation using heterogeneous drug-protein-disease network-based deep learning.APL bioengineering · 2025Article
- Article
- Population data study reveals pain as a possible protective factor against cerebrovascular disease in cancer patients.Scientific reports · 2024Article
- Gender and contemporary risk of adverse events in atrial fibrillation.European heart journal · 2024Article
- Common Genetic Factors and Pathways in Alzheimer's Disease and Ischemic Stroke: Evidences from GWAS.Genes · 2023Review
- Determining the Proportionality of Ischemic Stroke Risk Factors to Age.Journal of cardiovascular development and disease · 2023Article
- A review of risk concepts and models for predicting the risk of primary stroke.Frontiers in neuroinformatics · 2022Review
- Identifying risk factors and predicting stroke using Bayesian networks: Evidence from NHANES 2011-2020.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Age is one of the most important risk factors when it comes to stroke risk prediction. However, including age as a risk factor in a stroke prediction model can give rise to a number of difficulties. Age often dominates the risk score, and also not all risk factors contribute proportionally to stroke risk by age. In this study we investigate a number of common stroke risk factors, using Framingham heart study data from the NHLBI Biologic Specimen and Data Repository Information Coordinating Center to determine if they appear to contribute proportionally by age to a stroke risk score. As we find evidence that there is some non-proportionality by age, we then create a set of logistic regression risk models that each predict the 5 year stroke risk for a different age group. The age group models are shown to be better calibrated when compared to a model for all ages that includes age as a risk factor. This suggests that to get better predictions for stroke risk it may be necessary to consider alternative methods for including age in stroke risk prediction models that account for the non-proportionality of the other risk factors as age changes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.