Evidence map›Paper›PMID 35250805›Full record

ArticleFrontiers in neurology2022

Correlation Between Thrombus Signal Intensity and Aneurysm Wall Thickness in Partially Thrombosed Intracranial Aneurysms Using 7T Magnetization-Prepared Rapid Acquisition Gradient Echo Magnetic Resonance Imaging.

Taku Sato, Toshinori Matsushige, Bixia Chen, Oliver Gembruch, Philipp Dammann, Ramazan Jabbarli, Michael Forsting, Andreas Junker, Stefan Maderwald, Harald H Quick and 3 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Taku SatoDepartment of Neurosurgery, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Toshinori MatsushigeDepartment of Neurosurgery, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Bixia ChenDepartment of Neurosurgery, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Oliver GembruchDepartment of Neurosurgery, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Philipp DammannDepartment of Neurosurgery, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Ramazan JabbarliDepartment of Neurosurgery, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Michael ForstingDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Andreas JunkerInstitute of Neuropathology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Stefan MaderwaldErwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany.
Harald H QuickErwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany.
Mark E LaddErwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany.
Ulrich SureDepartment of Neurosurgery, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Karsten H WredeDepartment of Neurosurgery, University Hospital Essen, University Duisburg-Essen, Essen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study is to investigate the relationship between the thrombus signal intensity and aneurysm wall thickness in partially thrombosed intracranial aneurysms

methodsSixteen partially thrombosed intracranial aneurysms were evaluated using a 7T whole-body MR system with nonenhanced MPRAGE. To normalize the thrombus signal intensity, its highest signal intensity was compared to that of the anterior corpus callosum of the same subject, and the signal intensity ratio was calculated. The correlation between the thrombus signal intensity ratio and the thickness of the aneurysm wall was analyzed. Furthermore, aneurysmal histopathological specimens from six tissue samples were compared with radiological findings to detect any correlation.

resultsThe mean thrombus signal intensity ratio was 0.57 (standard error of the mean [SEM] 0.06, range 0.25-1.01). The mean thickness of the aneurysm wall was 1.25 (SEM 0.08, range 0.84-1.55) mm. The thrombus signal intensity ratio significantly correlated with the aneurysm wall thickness (

conclusionThe thrombus signal intensity ratio in partially thrombosed intracranial aneurysms correlated with aneurysm wall thickness and histologic features, indicating wall instability.

Indexed as

7T magnetic resonance imaginganeurysm wallmagnetization-prepared rapid acquisition gradient echopartially thrombosed intracranial aneurysmthrombus

Identifiers

PMID35250805
PMCPMC8894319

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.