Evidence map›Paper›PMID 35250799›Full record

ArticleFrontiers in neurology2022

Dissolution Effect of Alteplase on Arterial Blood Clot Model of Hypertensive Intracerebral Hemorrhage Patients

Xiaoming Jiang, Yongyu Lu, Xiaogang Hu, Xiaochun She

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Minimally invasive puncture combined with a high frequency of urokinase therapy improves outcomes in patients with HICH.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Xiaoming JiangDepartment of Neurosurgery, Rudong Hospital Affiliated to Nantong University, Nantong, China.
Yongyu LuDepartment of Neurosurgery, Haimen District People's Hospital, Nantong, China.
Xiaogang HuDepartment of Respiratory Medicine, Rudong Hospital Affiliated to Nantong University, Nantong, China.
Xiaochun SheDepartment of Neurosurgery, Rudong Hospital Affiliated to Nantong University, Nantong, China.
Nantong University · CNAffiliated Hospital of Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the dissolution effect of alteplase (rt-PA) on arterial blood clots of patients with hypertensive cerebral hemorrhage

methodsThe arterial blood of 35 patients with confirmed hypertensive cerebral hemorrhage were collected, centrifuged, and the serum was aspirated to prepare the blood clot model. The 0.125, 0.25, 0.5, 1, 2, and 3 mg t-PA, 20,000 U, and 40,000 U urokinase (u-PA) were taken for the corresponding blood clot for dissolution test. The blood clot volume and dissolution volume was measured at 0, 30, 60, 90, 120, and 150 min.

resultsWithout intervention, the blood clot volume of men was higher than that of women at 0, 30, 60, and 90 min (

conclusion

Indexed as

alteplasearterial blooddissolutionhypertensive cerebral hemorrhageurokinase

Identifiers

PMID35250799
PMCPMC8894242
OpenAlexW4213291832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.