Evidence map›Paper›PMID 35250789›Full record

ArticleFrontiers in neurology2021

Association Between Carotid Artery Perivascular Fat Density and Embolic Stroke of Undetermined Source.

Xiaohong Hu, Jianhui Chen, Huajun Fu, Yinjuan Chen, Daofeng Fan, Yangui Chen, Chaoxiong Shen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
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  7. Article
  8. Cognitive impairment in Parkinson's disease and other parkinsonian syndromes.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  9. Pericarotid Fat as a Marker of Cerebrovascular Risk.AJNR. American journal of neuroradiology · 2024
    Review
  10. Article
  11. The role of non-stenosing carotid artery plaques in embolic stroke of undetermined source, is it a silent offender? A review of literature.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Review
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Explainable Machine-Learning Model to Classify Culprit Calcified Carotid Plaque in Embolic Stroke of Undetermined Source.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaohong HuNeurology Department, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Jianhui ChenEmergency Department, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Huajun FuNeurology Department, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Yinjuan ChenNeurology Department, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Daofeng FanNeurology Department, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Yangui ChenNeurology Department, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Chaoxiong ShenNeurology Department, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Fujian Medical University · CNFirst Affiliated Hospital of Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study aims to retrospectively evaluate the association between pericarotid inflammation and the presence of embolic stroke of undetermined source (ESUS).

methodsIn total, 126 patients with ESUS and 118 patients with ischemic stroke from large artery atherosclerosis (LAA) were enrolled. All the patients underwent brain MRI and a neck CT angiography (CTA) examination. Reviewers were blinded to infarct location and stroke cause. Paired

resultsIn both the ESUS cases and LAA ischemic stroke cases, the pericarotid fat density around the carotid artery ipsilateral to the stroke significantly increased compared with contralateral stroke position in both the groups (ESUS cases -56.31 ± 18.70 vs. -67.31 ± 20.01,

conclusionWe found increased density in the fat surrounding carotid artery ipsilateral to stroke compared with contralateral in ESUS, suggesting the presence of an inflammatory reaction that extends beyond the vessel lumen in patients with ESUS with a risk factor profile similar to LAA strokes.

Indexed as

carotid arterycomputed tomography angiographyESUSLAA strokesperivascular fat density

Identifiers

PMID35250789
PMCPMC8894862
OpenAlexW4212912481

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.