ReviewFrontiers in human neuroscience2022
Understanding Language Reorganization With Neuroimaging: How Language Adapts to Different Focal Lesions and Insights Into Clinical Applications.
Review in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gut-brain axis and neuroplasticity in health and disease: a systematic review.La Radiologia medica · 2025Pooled it
- Identification of abnormal neural language networks by reading "brainprints" in patients with brain tumors.Neuroimage. Reports · 2026Article
- Broca's area, responsible for speech production, is regulated by lung function.Neural regeneration research · 2026Article
- Disrupted dynamics of transient brain states in patients with brain tumors: a co-activation pattern analysis of resting-state fMRI.La Radiologia medica · 2026Article
- Resting-State Coactivation Patterns of Language Reorganization in Brain Tumors.Neural plasticity · 2026Article
- The nonlinear trajectory of post-stroke aphasia recovery.Frontiers in human neuroscience · 2026Review
- Does white matter structure relate to hemispheric language lateralization? A systematic review.Brain communications · 2026Review
- Automated PACS-integrated pipeline for TractSeg-based segmentation of the arcuate fasciculus in patients with hearing loss.Frontiers in neuroscience · 2026Article
- The impact of glioblastoma on the contralesional hemisphere: insights from structural connectivity and cortical surface analysis.Neuroradiology · 2025Article
- Brain-Inspired Multisensory Learning: A Systematic Review of Neuroplasticity and Cognitive Outcomes in Adult Multicultural and Second Language Acquisition.Biomimetics (Basel, Switzerland) · 2025Review
- Cognitive Control Network and Language Reorganization in Patients with Brain Tumors.AJNR. American journal of neuroradiology · 2025Article
- A comparison of diffusion tensor imaging tractography approaches to identify the Frontal Aslant Tract in neurosurgical patients.Frontiers in neuroscience · 2025Article
- Language neuroscience in the operating room: neurosurgical considerations for multilingual brain tumor patients.Frontiers in oncology · 2025Review
- Case Report: A personalized model of care for surgical resection of complex brain tumor with atypical language dominance.Frontiers in neuroscience · 2025Article
- Radiosurgery for Hypothalamic Gliomas: A Case Report and Clinical Guidelines Form a Neurosurgical Center of Excellence.Journal of personalized medicine · 2024Article
- Insights into epileptic aphasia: Intracranial recordings in a child with a left insular ganglioglioma.Epilepsy & behavior reports · 2024Article
- Association of Lack of Speech Arrest During Cortical Stimulation With Interhemispheric Reorganization of the Functional Language Network in Patients With Brain Tumors.AJR. American journal of roentgenology · 2023Article
- Challenging the supremacy of fMRI in assessing language lateralization.European radiology · 2023Article
- Talking about speaking: what do we know about language reorganization in brain tumors before surgery.European radiology · 2023Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
When the language-dominant hemisphere is damaged by a focal lesion, the brain may reorganize the language network through functional and structural changes known as adaptive plasticity. Adaptive plasticity is documented for triggers including ischemic, tumoral, and epileptic focal lesions, with effects in clinical practice. Many questions remain regarding language plasticity. Different lesions may induce different patterns of reorganization depending on pathologic features, location in the brain, and timing of onset. Neuroimaging provides insights into language plasticity due to its non-invasiveness, ability to image the whole brain, and large-scale implementation. This review provides an overview of language plasticity on MRI with insights for patient care. First, we describe the structural and functional language network as depicted by neuroimaging. Second, we explore language reorganization triggered by stroke, brain tumors, and epileptic lesions and analyze applications in clinical diagnosis and treatment planning. By comparing different focal lesions, we investigate determinants of language plasticity including lesion location and timing of onset, longitudinal evolution of reorganization, and the relationship between structural and functional changes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.