Evidence map›Paper›PMID 35250453›Full record

ArticleFrontiers in neuroscience2022

The Effect and Mechanism of Transcranial Direct Current Stimulation on Episodic Memory in Patients With Mild Cognitive Impairment.

Jun Gu, Da Li, Zhaohui Li, Yuan Guo, Fuqiang Qian, Ying Wang, Li Tang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 5 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 5 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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  6. Trial
  7. A meta-analysis of the effect of non-invasive neuromodulation techniques on improving cognitive function in patients with Alzheimer's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jun GuDepartment of Mental Rehabilitation, Wuxi Mental Health Center, Wuxi, China.
Da LiDepartment of Mental Rehabilitation, Wuxi Mental Health Center, Wuxi, China.
Zhaohui LiDepartment of Neurorehabilitation, Wuxi Tongren Rehabilitation Hospital, Wuxi, China.
Yuan GuoPsychometric Laboratory, Wuxi Mental Health Center, Wuxi, China.
Fuqiang QianMedical Administration Department, Wuxi Mental Health Center, Wuxi, China.
Ying WangDepartment of Psychiatry, Wuxi Mental Health Center, Wuxi, China.
Li TangDepartment of Psychiatry, Wuxi Mental Health Center, Wuxi, China.
Jiangxi Mental Health Center · CNTongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate the efficacy of transcranial direct current stimulation (tDCS) on episodic memory in patients with mild cognitive impairment (MCI) and analyze the neural mechanism of tDCS therapy from the perspective of neuroelectrophysiological parameters.

methodsForty MCI patients were recruited and randomly divided into a sham group (

resultsThe two groups showed no significant difference in any of the assessed parameters at pre-treatment (

conclusiontDCS improved episodic memory in MCI patients, and the effect lasted for 4 weeks. Changes in ERP (P300) suggested that tDCS could promote changes in brain function.

Indexed as

event related potential (ERP)mild cognitive impairment (MCI)Montreal Cognitive Assessment Scale (MoCA)transcranial direct current stimulation (tDCS)Wechsler Memory Scale (WMS)

Identifiers

PMID35250453
PMCPMC8891804
OpenAlexW4213294163

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.