Evidence map›Paper›PMID 35250450›Full record

ArticleFrontiers in neuroscience2022

Gut Microbial Characteristics of Adult Patients With Epilepsy.

Lian Dong, Qian Zheng, Yongran Cheng, Mengyun Zhou, Mingwei Wang, Jianwei Xu, Zucai Xu, Guofeng Wu, Yunli Yu, Lan Ye and 1 more

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lian DongDepartment of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Qian ZhengDepartment of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Yongran ChengSchool of Public Health, Hangzhou Medical College, Hangzhou, China.
Mengyun ZhouDepartment of Molecular and Cellular Physiology, Shinshu University School of Medicine, Nagano, Japan.
Mingwei WangDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Jianwei XuNational Guizhou Joint Engineering Laboratory for Cell Engineering and Biomedicine Technique, Guizhou Province Key Laboratory of Regenerative Medicine, Center for Tissue Engineering and Stem Cell Research, Guizhou Medical University, Guiyang, China.
Zucai XuDepartment of Neurology, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Guofeng WuDepartment of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Yunli YuDepartment of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Lan YeThe Medical Function Laboratory of Experimental Teaching Center of Basic Medicine, Guizhou Medical University, Guiyang, China.
Zhanhui FengDepartment of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo characterize the intestinal flora of patients with epilepsy and its correlation with epilepsy.

methodsPatients with ages > 18 years were consecutively enrolled from the outpatient department, Affiliated Hospital of Guizhou Medical University from January 2018 to December 2019. A total of 71 subjects were recruited, including epilepsy patients (

resultsLEfSe analysis showed that

conclusionThere were significant differences in the composition and functional pathways of gut flora between epilepsy patients and patient family members. The

Indexed as

16S rRNAbiomarkersepilepsygut microbiotamicrobiota-gut-brain axisPICRUSt

Identifiers

PMID35250450
PMCPMC8888681

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.