ArticleFrontiers in neuroscience2021
Decreased Functional Connectivities of Low-Degree Level Rich Club Organization and Caudate in Post-stroke Cognitive Impairment Based on Resting-State fMRI and Radiomics Features.
Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Resting-state functional connectivity alterations in post-stroke cognitive impairment: a systematic review.Brain imaging and behavior · 2025Pooled it
- Topological Alterations of Functional Brain Networks in Post-Stroke Cognitive Impairment: a Graph-Theoretical Study.Clinical neuroradiology · 2026Article
- Structural connectome and cognitive performance in young stroke survivors.Scientific reports · 2026Article
- Decoding Post-Stroke Cognitive Impairment After Acute Basal Ganglia Infarction: The Synergistic Role of Functional Segregation and Integration in an SVM fMRI Framework.CNS neuroscience & therapeutics · 2026Article
- Functional connectivity alterations in patients with poststroke cognitive impairment: A resting-state functional magnetic resonance imaging study.World journal of radiology · 2026Article
- Combined Maternal Immune Activation and Prenatal Intermittent Hypoxic Stress Lead to Developmental Motor Deficits in Rats: a Two-hit Animal Model for Cerebral Palsy Across Different Age Trajectories.Molecular neurobiology · 2025Article
- Acupuncture for Poststroke Cognitive Impairment Based on Default Mode Network Analysis: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2025Article
- The application of radiomics in the diagnosis and evaluation of cognitive impairment related to neurological diseases.Frontiers in neuroscience · 2025Review
- Blood-based biomarkers and neuroimaging for early detection of post-stroke cognitive impairment: current evidence and synergistic prospects.Frontiers in neurology · 2025Review
- Altered brain dynamics in post-stroke cognitive and motor dysfunction.Frontiers in aging neuroscience · 2025Article
- Identification of a cognitive network with effective connectivity to post-stroke cognitive impairment.Cognitive neurodynamics · 2024Article
- Abnormal dynamic functional connectivity in young nondisabling intracerebral hemorrhage patients.Annals of clinical and translational neurology · 2024Article
- Disturbed functional connectivity and topological properties of the frontal lobe in minimally conscious state based on resting-state fNIRS.Frontiers in neuroscience · 2023Article
- Prognostic nomogram for the outcomes in acute stroke patients with intravenous thrombolysis.Frontiers in neuroscience · 2022Article
- Regional homogeneity alterations in multifrequency bands in patients with basal ganglia stroke: A resting-state functional magnetic resonance imaging study.Frontiers in aging neuroscience · 2022Article
- Adjunctive PC6 magnetic stimulation with rTMS over left DLPFC for post-stroke cognitive impairment: a protocol for fNIRS-fMRI randomized controlled trial.Frontiers in neurologyArticle
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStroke is an important cause of cognitive impairment. Rich club organization, a highly interconnected network brain core region, is closely related to cognition. We hypothesized that the disturbance of rich club organization exists in patients with post-stroke cognitive impairment (PSCI).
methodsWe collected data on resting-state functional magnetic resonance imaging (rs-fMRI) with 21 healthy controls (HC), 16 hemorrhagic stroke (hPSCI), and 21 infarct stroke (iPSCI). 3D shape features and first-order statistics of stroke lesions were extracted using 3D slicer software. Additionally, we assessed cognitive function using the Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE).
resultsNormalized rich club coefficients were higher in hPSCI and iPSCI than HC at low-degree
conclusionThis study reveals the disrupted low-degree level rich club organization and relatively preserved functional core network in PSCI patients. Decreased feeder and local connections in cognition-related networks (DMN, SN, CN, and ORB), particularly involving the caudate nucleus, may offer insight into pathological mechanism of PSCI patients. The shape and signal features of stroke lesions may provide an essential clue for the damage of functional connectivity and the whole brain networks.
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