Trial reportJournal of sports science & medicine2022
Early Superimposed NMES Training is Effective to Improve Strength and Function Following ACL Reconstruction with Hamstring Graft regardless of Tendon Regeneration.
Trial report in Journal of sports science & medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07171346 (Effects on Patient Outcomes With Post-Operative Use of Zynex Neuromuscular Electrical Stimulation), which is not on this map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects on Patient Outcomes With Post-Operative Use of Zynex Neuromuscular Electrical Stimulation (NMES): Zynex-25
Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Muscle Synergy Analysis of Different PAPE Protocols on Side Kick Performance in Elite Sanda Athletes: A Repeated Measures Study.Sensors (Basel, Switzerland) · 2026Trial
- From physical modalities to energy-responsive biomaterials: Current strategies and challenges in tendon-to-bone healing.Bioactive materials · 2026Review
- Progressive Early Mobilization and Its Impact on Pain and Function After Lumbar Vertebral Compression Fracture: A Retrospective Study Based on the Oswestry Disability Index.Journal of pain research · 2026Article
- Rehabilitation guidelines after autograft anterior cruciate ligament reconstruction need more graft-specific exercise recommendations-A scoping review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Evolution of pre- and post-operative balance characteristics in patients undergoing anterior cruciate ligament reconstruction: implications for rehabilitation.Frontiers in bioengineering and biotechnology · 2026Article
- Effects of neuromuscular electrical stimulation on neuromuscular function and muscle quality in patient following anterior cruciate ligament reconstruction.Journal of exercise rehabilitation · 2025Article
- The Effect of Physiotherapy on Arthrogenic Muscle Inhibition After ACL Injury or Reconstruction: A Systematic Review.Life (Basel, Switzerland) · 2024Review
- Frequency-dependent effects of superimposed NMES on spinal excitability in upper and lower limb muscles.Heliyon · 2024Article
- Adjustments in the motor unit discharge behavior following neuromuscular electrical stimulation compared to voluntary contractions.Frontiers in physiology · 2023Article
- NMES superimposed on movement is equally effective as heavy slow resistance training in patellar tendinopathy.Journal of musculoskeletal & neuronal interactions · 2022Article
- Short histological kaleidoscope - recent findings in histology. Part V. About tendons, ligaments, and cartilages.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieReview
- Can we rebuild what has been taken? A narrative review of biological and functional consequences of hamstring tendon harvest in ACL surgery.Science progressReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study aimed at investigating the effects of neuromuscular electrical stimulation superimposed on functional exercises (NMES+) early after anterior cruciate ligament reconstruction (ACLr) with hamstring graft, on muscle strength, knee function, and morphology of thigh muscles and harvested tendons. Thirty-four participants were randomly allocated to either NMES+ group, who received standard rehabilitation with additional NMES of knee flexor and extensor muscles, superimposed on functional movements, or to a control group, who received no additional training (NAT) to traditional rehabilitation. Participants were assessed 15 (T1), 30 (T2), 60 (T3), 90 (T4) and at a mean of 380 days (T5) after ACLr. Knee strength of flexors and extensors was measured at T3, T4 and T5. Lower limb loading asymmetry was measured during a sit-to-stand-to-sit movement at T1, T2, T3, T4 and T5, and a countermovement-jump at T4 and T5. An MRI was performed at T5 to assess morphology of thigh muscles and regeneration of the harvested tendons. NMES+ showed higher muscle strength for the hamstrings (T4, T5) and the quadriceps (T3, T4, T5), higher loading symmetry during stand-to-sit (T2, T3, T4, T5), sit-to-stand (T3, T4) and countermovement-jump (T5) than NAT. No differences were found between-groups for morphology of muscles and tendons, nor in regeneration of harvested tendons. NMES+ early after ACLr with hamstring graft improves muscle strength and knee function in the short- and long-term after surgery, regardless of tendon regeneration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.