Evidence map›Paper›PMID 35250091›Full record

ArticleJournal of molecular structure2022

Synthesis, crystal structure, DFT and molecular docking studies of N-acetyl-2,4-[diaryl-3-azabicyclo[3.3.1]nonan-9-yl]-9-spiro-4'-acetyl-2'-(acetylamino)-4',9-dihydro-[1',3',4']-thiadiazoles: A potential SARS-nCoV-2 Mpro (COVID-19) inhibitor.

Ramachandran Rajamanickam, Rani Mannangatty, Jayanthi Sampathkumar, Kabilan Senthamaraikannan, Barathi Diravidamani

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular structure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ramachandran RajamanickamDepartment of Chemistry, PGP College of Arts and Science (Affiliated to Periyar University-Salem), Namakkal, 637 207, Tamil Nadu, India.
Rani MannangattyDepartment of Chemistry, Annamalai University, Annamalainagar, 608 002, Tamil Nadu, India.
Jayanthi SampathkumarDepartment of Chemistry, N.K.R Government Arts college for Women (Affiliated to Periyar University-Salem), Namakkal, 637 001, Tamil Nadu, India.
Kabilan SenthamaraikannanDepartment of Chemistry, Annamalai University, Annamalainagar, 608 002, Tamil Nadu, India.
Barathi DiravidamaniDepartment of Physics, N.K.R Government Arts college for Women (Affiliated to Periyar University-Salem), Namakkal, 637 001, Tamil Nadu, India.
Periyar University · INAnnamalai University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, we describe the synthesis and crystal structure analysis of N-acetyl-2,4-[diphenyl-3-azabicyclo[3.3.1]nonan-9-yl]-9-spiro-4'-acetyl-2'-(acetylamino)-4',9-dihydro-[1',3',4']-thiadiazole (

Indexed as

Azabicyclo[3.3.1]nonan-9-onesChalcogen bondMolecular dockingSARS-nCoV-2 MproSpiro thiadiazoles

Identifiers

PMID35250091
PMCPMC8888462
OpenAlexW4214815173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.