Evidence map›Paper›PMID 35250041›Full record

ArticleFuel (London, England)2022

Characterization of Compositional Variability in Petroleum Substances.

Alina T Roman-Hubers, Alexandra C Cordova, Arlean M Rohde, Weihsueh A Chiu, Thomas J McDonald, Fred A Wright, James N Dodds, Erin S Baker, Ivan Rusyn

Abstract read
In one paragraph

Article in Fuel (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alina T Roman-HubersDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77843, United States.
Alexandra C CordovaDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77843, United States.
Arlean M RohdeDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77843, United States.
Weihsueh A ChiuDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77843, United States.
Thomas J McDonaldDepartments of Environmental and Occupational Health, Texas A&M University, College Station, Texas 77843, United States.
Fred A WrightDepartments of Statistics and Biological Sciences, Raleigh, North Carolina 27695, United States.
James N DoddsDepartment of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, United States.
Erin S BakerDepartment of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, United States.
Ivan RusynDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77843, United States.

Funding

Single cell, multi-parametric high throughput platform to classify endocrine disruptor potential of mixturesP42ES027704 · NIEHS · TEXAS A&M UNIVERSITY · PI Weihsueh A Chiu · 2017 to 2026
$21.2M
Texas A&M Center for Environmental Health Research (TiCER)P30ES029067 · NIEHS · TEXAS A&M UNIVERSITY · PI Galen Newman · 2019 to 2026
$13.0M
Regulatory Science in Environmental Health and ToxicologyT32ES026568 · NIEHS · TEXAS A&M UNIVERSITY · PI Weihsueh A Chiu, Natalie M Johnson · 2016 to 2026
$3.8M
NIEHS NIH HHS P30 ES029067NIEHS NIH HHS P42 ES027704NIEHS NIH HHS T32 ES026568
6 · The paper itself

Abstract

In the process of registration of substances of Unknown or Variable Composition, Complex Reaction Products or Biological Materials (UVCBs), information sufficient to enable substance identification must be provided. Substance identification for UVCBs formed through petroleum refining is particularly challenging due to their chemical complexity, as well as variability in refining process conditions and composition of the feedstocks. This study aimed to characterize compositional variability of petroleum UVCBs both within and across product categories. We utilized ion mobility spectrometry (IMS)-MS as a technique to evaluate detailed chemical composition of independent production cycle-derived samples of 6 petroleum products from 3 manufacturing categories (heavy aromatic, hydrotreated light paraffinic, and hydrotreated heavy paraffinic). Atmospheric pressure photoionization and drift tube IMS-MS were used to identify structurally related compounds and quantified between- and within-product variability. In addition, we determined both individual molecules and hydrocarbon blocks that were most variable in samples from different production cycles. We found that detailed chemical compositional data on petroleum UVCBs obtained from IMS-MS can provide the information necessary for hazard and risk characterization in terms of quantifying the variability of the products in a manufacturing category, as well as in subsequent production cycles of the same product.

Identifiers

PMID35250041
PMCPMC8896784

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.