Evidence map›Paper›PMID 35249811›Full record

ReviewSeminars in cell & developmental biology2023

Seminars in cell and development biology on histone variants remodelers of H2A variants associated with heterochromatin.

Frédéric Berger, Kathrin Muegge, Eric J Richards

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Frédéric BergerGregor Mendel Institute, Austrian Academy of Sciences, Vienna BioCenter, Dr. Bohr-Gasse 3, 1030 Vienna, Austria. Electronic address: frederic.berger@gmi.oeaw.ac.at.
Kathrin MueggeEpigenetics Section, Frederick National Laboratory for Cancer Research in the Mouse Cancer Genetics Program, National Cancer Institute, Frederick, MD, USA. Electronic address: kathrin.muegge@nih.gov.
Eric J RichardsBoyce Thompson Institute, 533 Tower Road, Ithaca, NY, USA. Electronic address: ejr77@btiscience.org.
Cornell University · USFrederick National Laboratory for Cancer Research · USGregor Mendel Institute of Molecular Plant Biology · AT

Funding

Epigenetic control during embryogenesisZIABC010014 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI MUEGGE, KATHRIN · 2009 to 2025
$18.1M
GENE REARRANGEMENT AND DNA REPAIRZ01BC010014 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI MUEGGE, KATHRIN · 1996 to 2008
$1.5M
Austrian Science Fund FWF P 32054Austrian Science Fund FWF P 33380Intramural NIH HHS Z01 BC010014
6 · The paper itself

Abstract

Variants of the histone H2A occupy distinct locations in the genome. There is relatively little known about the mechanisms responsible for deposition of specific H2A variants. Notable exceptions are chromatin remodelers that control the dynamics of H2A.Z at promoters. Here we review the steps that identified the role of a specific class of chromatin remodelers, including LSH and DDM1 that deposit the variants macroH2A in mammals and H2A.W in plants, respectively. The function of these remodelers in heterochromatin is discussed together with their multiple roles in genome stability.

Indexed as

HeterochromatinHistonesAnimalsBiologyChromatinMammalsNucleosomesPromoter Regions, GeneticChromatinHeterochromatinHistonesNucleosomesChromatinEpigeneticsHistone variantsRemodelersTransposons

Identifiers

PMID35249811
PMCPMC9440159
OpenAlexW4214931848

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.