Evidence map›Paper›PMID 35249225›Full record

ArticleThe Journal of physiology2022

Exercise training remodels subcutaneous adipose tissue in adults with obesity even without weight loss.

Cheehoon Ahn, Benjamin J Ryan, Michael W Schleh, Pallavi Varshney, Alison C Ludzki, Jenna B Gillen, Douglas W Van Pelt, Lisa M Pitchford, Suzette M Howton, Thomas Rode and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Relationship between aerobic fitness and adipose tissue insulin resistance.American journal of physiology. Endocrinology and metabolism · 2026
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  5. Beyond weight loss: the value of physical activity and exercise for improving cardiometabolic risk factors in individuals with overweight and obesity.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Cheehoon AhnSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-4140-125X
Benjamin J RyanSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0001-5848-6988
Michael W SchlehSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Pallavi VarshneySubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Alison C LudzkiSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-6967-034X
Jenna B GillenSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0001-7974-5395
Douglas W Van PeltSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0001-9594-604X
Lisa M PitchfordSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Suzette M HowtonSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Thomas RodeSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Scott L HummelDivision of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-0924-3135
Charles F BurantDivision of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Jonathan P LittleSchool of Health and Exercise Sciences, University of British Columbia, Kelowna, BC, Canada.ORCID 0000-0002-9796-2008
Jeffrey F HorowitzSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-3851-777X
University of Michigan · USUniversity of British Columbia · CAUniversity of Toronto · CA

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Kanakadurga Singer · 2010 to 2026
$20.3M
Statistics and Bioinformatics Core - WangU24DK097153 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BURANT, CHARLES F · 2012 to 2017
$10.1M
TRAINING PROGRAM IN ENDOCRINOLOGY AND METABOLISM.T32DK007245 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RICHARD J. AUCHUS · 1986 to 2026
$7.2M
Insulin sensitivity and fatty acid partitioning in skeletal muscle after exerciseR01DK077966 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOROWITZ, JEFFREY F · 2010 to 2020
$4.9M
The role of iron in adipose tissue lipolysis, systemic fatty acid mobilization, and insulin resistance in obese humansF32DK117522 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RYAN, BENJAMIN · 2018 to 2020
$87k
NIDDK NIH HHS F32 DK117522NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK089503NIDDK NIH HHS R01 DK077966NIDDK NIH HHS T32 DK007245NIDDK NIH HHS U24 DK097153
6 · The paper itself

Abstract

Excessive adipose tissue mass underlies much of the metabolic health complications in obesity. Although exercise training is known to improve metabolic health in individuals with obesity, the effects of exercise training without weight loss on adipose tissue structure and metabolic function remain unclear. Thirty-six adults with obesity (body mass index = 33 ± 3 kg · m

Indexed as

ExerciseObesityAdipose TissueAdultFatty AcidsHumansSubcutaneous FatWeight LossFatty Acidsadipose tissueexercise traininghigh-intensity interval training

Identifiers

PMID35249225
PMCPMC9058215
OpenAlexW4220729385

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.