Evidence map›Paper›PMID 35249167›Full record

ReviewMolecular biology reports2022

Association of severity and mortality of Covid-19 cases among acute kidney injury and sexual dimorphism.

Mukul Kumar Singh, Mayank Jain, Hari Shyam, Dinesh Kumar Sahu, Archana Mishra, Pratap Shankar, Shailendra Kumar, Vishwajeet Singh

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mukul Kumar Singh *Department of Urology, King George's Medical University, Chowk, Lucknow, Uttar Pradesh, 226003, India.
Mayank Jain *Department of Thoracic Surgery, King George's Medical University, Lucknow, UP, 226003, India.
Hari Shyam *Department of Thoracic Surgery, King George's Medical University, Lucknow, UP, 226003, India.
Dinesh Kumar Sahu *Super Speciality Paediatric Hospital & Post Graduate Teaching Institute, Noida, UP, 201301, India.
Archana MishraDepartment of Thoracic Surgery, King George's Medical University, Lucknow, UP, 226003, India.
Pratap ShankarDepartment of Centre for Advance Research, King George's Medical University, Lucknow, UP, 226003, India.
Shailendra KumarDepartment of Thoracic Surgery, King George's Medical University, Lucknow, UP, 226003, India.
Vishwajeet SinghDepartment of Urology, King George's Medical University, Chowk, Lucknow, Uttar Pradesh, 226003, India. drvishwajeet68@gmail.com.ORCID http://orcid.org/0000-0003-1074-4647
King George's Medical University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe outbreak of coronavirus disease 2019 (Covid-19) severely impacted global health and economic status. The native receptor-ligand interaction of Angiotensin-converting enzyme 2 (ACE2) and S protein induces host cell pathogenesis via immunosuppression. MATERIAL AND

methodsThe emerging evidence reports the sex disparity in Covid-19 induced mortality rate which affects abundantly men population. Although the biological interaction of Covid-19 with receptor upregulates the viral genome protein interactions and initiates the predictive multiorgan failure followed by acute kidney injury (AKI) in Covid-19 infected male population.

conclusionBesides, the knowledge and lessons learned from the study depict that cellular and molecular links may explain the risk and severity of Covid-19 and AKI in the male population and lead to management of Covid-19 induced AKI. Therefore, this review explored the pathways associated with the pathogenesis of two diseased conditions with sex disparity.

Indexed as

Acute Kidney InjuryCOVID-19HumansMaleSARS-CoV-2Sex CharacteristicsAKICovid-19ImmunosuppressionPathogenesisSex-disparity

Identifiers

PMID35249167
PMCPMC8898193
OpenAlexW4220775579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.