Evidence map›Paper›PMID 35249159›Full record

Observational studyJournal of cancer research and clinical oncology2022

Early detection of oral cancer: a key role for dentists?

Katrin Hertrampf, Martina Jürgensen, Stefanie Wahl, Eva Baumann, Hans-Jürgen Wenz, Jörg Wiltfang, Annika Waldmann

Registry-linked trialAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of cancer research and clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06231537 (Visual Oral Examination in Primary Health Care for Early Detection of Oral Cancer), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06231537 nacompletednot on this mapstarted 2023, after this paper: background citation

Visual Oral Examination in Primary Health Care for Early Detection of Oral Cancer: Targeting High-Risk Individuals in the Municipality of Rio de Janeiro

TypeinterventionalSponsorUniversidade Federal do Rio de JaneiroRan2023 to 2024Enrolled1,152ConditionsMouth NeoplasmsArmsVisual oral examination
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katrin HertrampfDepartment of Oral and Maxillofacial Surgery, University Hospital of Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, Building B, 24105, Kiel, Germany. hertrampf@mkg.uni-kiel.de.ORCID http://orcid.org/0000-0003-1589-0619
Martina JürgensenInstitute of Social Medicine and Epidemiology, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
Stefanie WahlDepartment of Journalism and Communication Research, Hanover University of Music, Drama and Media, Expo Plaza 12, 30539, Hanover, Germany.
Eva BaumannDepartment of Journalism and Communication Research, Hanover University of Music, Drama and Media, Expo Plaza 12, 30539, Hanover, Germany.
Hans-Jürgen WenzDepartment of Prosthodontics, Propaedeutics and Dental Materials, University Hospital of Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str.3, Building B, 24105, Kiel, Germany.
Jörg WiltfangDepartment of Oral and Maxillofacial Surgery, University Hospital of Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, Building B, 24105, Kiel, Germany.
Annika WaldmannInstitute of Social Medicine and Epidemiology, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe majority of suspected malignant changes in the oral mucosa are detected by dentists in private practice. Statements regarding the effectiveness of visual examination of the oral cavity for early detection are not necessarily transferable between different health care systems. Our clinical-epidemiological and methodological aim was thus to conduct a prospective regional study in dental practices under everyday conditions, assess the frequency and type of oral mucosal changes, and evaluate the dental examination methodology.

methodsA prospective observational study was conducted, combining a feasibility study of early detection of oral cancer and its documentation with phase I 'modelling' to conceptualize complex interventions in health services research. Dentists in private practice continuously recruited patients over 6 months and used two different sheets for the documentation of suspicious lesions. Statistical analysis involved descriptive statistics and tests for differences (Welch test) or association (Chi-squared test).

resultsTwenty-five dentists (mean age: 50 years, 24% females) participated in this study. Eleven dentists achieved the overall aim of recruiting 200 patients. Around 4200 patients (mean age: 52 years, 57.5% females) participated. The prevalence of suspicious lesions was 8.5%.

conclusionIt became apparent that a study in cooperation with dentists in private practice to generate clinical-epidemiological data on the early detection of oral mucosal lesions under everyday conditions can be carried out successfully. Further studies with a corresponding level of evidence should be carried out to be able to draw conclusions about the effectiveness of the early detection measure under everyday practice conditions.

Indexed as

DentistsMouth NeoplasmsAttitude of Health PersonnelEarly Detection of CancerFemaleHumansMaleMiddle AgedProspective StudiesSurveys and QuestionnairesDentistsEarly detectionFeasibilityOral cancerScreening

Identifiers

PMID35249159
PMCPMC9114047

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.