Observational studyObesity facts2022
Obesity in Older Adults and Associations with Cardiovascular Structure and Function.
Observational study in Obesity facts, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02791139 (Association of Midlife Dietary and Lifestyle Factors on Cardiac Functional Changes in the Elderly), which is not on this map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Association of Midlife Dietary and Lifestyle Factors on Cardiac Functional Changes in the Elderly
Who cites it
13 citing papers in PubMed, 16 citations in OpenAlex.
- Application of the Lancet Commission Criteria for the Diagnosis of Obesity to a Clinical Trials Population: The LEAP Trial.Obesity (Silver Spring, Md.) · 2026Trial
- Warm-Up and Handgrip Strength in Physically Inactive Chilean Older Females According to Baseline Nutritional Status.International journal of environmental research and public health · 2022Trial
- Nutritional Status, Abdominal Obesity, and Predictors of BMI Categories Among Community-Dwelling Older Adults in Southern Thailand: A Cross-Sectional Study.International journal of environmental research and public health · 2026Article
- A machine learning approach to conglomerate multi-domain features of cardiac aging.European heart journal. Digital health · 2026Article
- Dynamic associations of BMI-metabolic phenotype transitions with incident cardiovascular disease in middle-aged and elderly adults: a longitudinal cohort study.BMC cardiovascular disorders · 2026Article
- Cardiometabolic Index, BMI, Waist Circumference, and Cardiometabolic Multimorbidity Risk in Older Adults.Geriatrics (Basel, Switzerland) · 2025Article
- Associations between muscle quality index and cardiac function in older adults with sarcopenia and obesity.Aging clinical and experimental research · 2025Article
- Overweight and Obesity and Multimorbidity in Community-Living Older Persons in the Philippines.Journal of the ASEAN Federation of Endocrine Societies · 2025Article
- The effect of intermittent fasting on preventing obesity-related early aging from a molecular and cellular perspective.Journal of medicine and life · 2024Review
- Effectiveness of Spironolactone in Terms of Galectin-3 Levels in Patients with Heart Failure with a Reduced Ejection Fraction in the Vietnamese Population.Healthcare (Basel, Switzerland) · 2023Article
- Effect of psychosocial motivations and technology on physical activity behaviours among community older men and women.BMC geriatrics · 2022Article
- Cardio-sarcopenia: A syndrome of concern in aging.Frontiers in medicine · 2022Article
- Global, regional, and national burden of disease for high BMI-related ischemic stroke in people aged 70 and older: trend analysis from 1990 to 2021 and projections for 2044.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
introductionBody mass index (BMI), despite being widely used as a marker of obesity, fails to fully capture cardiovascular risks as it is an insufficient biomarker of abdominal adiposity, unlike waist circumference (WC). We aimed to characterize associations between BMI and WC with cardiovascular structure and function in older adults.
methodsAmong an observational cohort study of a community of older adults, transthoracic echocardiography determined cardiovascular structure and function, while aerobic capacity was determined by peak oxygen uptake (VO2) metrics. The cut-offs for obesity were 27.5 kg/m2 for BMI, and >90 cm for males and >80 cm for females for WC.
resultsOf 970 older adults without cardiovascular disease (mean age 73 ± 4 years, 432 [44%] males), 124 (12.8%) were obese by BMI definition while 347 (35.7%) were obese by WC definition. Inter-definitional agreement was fair (Cohen's κ = 0.345). Unlike the BMI definition, participants defined as obese by WC were more likely to be women (65% vs. 50%, p < 0.001), older (65 ± 11 vs. 63 ± 14 years, p = 0.007), and had lower handgrip strength (24 ± 0.6 vs. 26 ± 0.4 kg, p = 0.022). Across BMI categories, high WC was associated with more impaired myocardial relaxation (E/A), and VO2 measurements (all p < 0.05). Among those with low BMI, high WC was associated with larger left atrial (LA) volumes (p = 0.003). WC, but not BMI, was independently associated with E/A (β = -0.114, SE -0.114 ± 0.024, p < 0.001) in regression analysis.
conclusionWC identified a higher prevalence of obesity, possibly related to central adiposity. Across BMI categories, WC identified more adverse measurements in E/A, aerobic capacity, and LA structure.
trial registrationClinicalTrials.gov Identifier: NCT02791139.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.