Evidence map›Paper›PMID 35248193›Full record

ReviewProgress in brain research2022

Speech dysfunction, cognition, and Parkinson's disease.

Andrea Rohl, Stephanie Gutierrez, Karim Johari, Jeremy Greenlee, Kris Tjaden, Angela Roberts

Open access · greenAbstract readReview
In one paragraph

Review in Progress in brain research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
23.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Parkinson's disease and reading performance.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Subthalamic nucleus-language network connectivity predicts dopaminergic modulation of speech function in Parkinson's disease.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Andrea RohlDepartment of Neurosurgery, University of Iowa, Iowa City, IA, United States.
Stephanie GutierrezRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL, United States.
Karim JohariDepartment of Neurosurgery, University of Iowa, Iowa City, IA, United States.
Jeremy GreenleeDepartment of Neurosurgery, University of Iowa, Iowa City, IA, United States.
Kris TjadenDepartment of Communicative Disorders and Sciences, University at Buffalo, Buffalo, NY, United States.
Angela RobertsRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL, United States; Department of Computer Science, Western University, London, ON, Canada. Electronic address: angela.roberts@uwo.ca.
University of Iowa · USNorthwestern University · USUniversity at Buffalo, State University of New York · US

Funding

Role of Subthalamic nucleus in Speech and Movement among people with Parkinson’s as Revealed by Intraoperative Recordings and Deep Brain StimulationR01DC017718 · NIDCD · UNIVERSITY OF IOWA · PI GREENLEE, JEREMY · 2020 to 2024
$3.1M
Phase 2 Development of a Spoken Language Biomarker of Cognitive Impairment in Parkinson's DiseaseR21DC017255 · NIDCD · NORTHWESTERN UNIVERSITY · PI ROBERTS, ANGELA CHRISTINE · 2019 to 2021
$489k
NIDCD NIH HHS R01 DC017718NIDCD NIH HHS R21 DC017255
6 · The paper itself

Abstract

Communication difficulties are a ubiquitous symptom of Parkinson's disease and include changes to both motor speech and language systems. Communication challenges are a significant driver of lower quality of life. They are associated with decreased communication participation, social withdrawal, and increased risks for social isolation and stigmatization in persons with Parkinson's disease. Recent theoretical advances and experimental evidence underscore the intersection of cognition and motor processes in speech production and their impact on spoken language. This chapter overviews a growing evidence base demonstrating that cognitive impairments interact with motor changes in Parkinson's disease to negatively affect communication abilities in myriad ways, at all stages of the disease, both in the absence and presence of dementia. The chapter highlights common PD interventions (pharmacological, surgical, and non-pharmacological) and how cognitive influences on speech production outcomes are considered in each.

Indexed as

Parkinson DiseaseSpeechCognitionHumansLanguageQuality of LifeCommunicationCommunication participationConversationParkinson's diseaseSpeechSpeech-language therapySpoken languageVoice

Identifiers

PMID35248193
PMCPMC11321444
OpenAlexW4210884241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.