Evidence map›Paper›PMID 35248103›Full record

Observational studySubstance abuse treatment, prevention, and policy2022

Concerns among people who use opioids during the COVID-19 pandemic: a natural language processing analysis of social media posts.

Abeed Sarker, Nisha Nataraj, Wesley Siu, Sabrina Li, Christopher M Jones, Steven A Sumner

Abstract readObservational Study
In one paragraph

Observational study in Substance abuse treatment, prevention, and policy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. User profiles of young breast cancer survivors on Chinese social media: machine learning-based text mining analysis study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Article
  3. Mining Social Media for Barriers to Opioid Recovery with LLMs.Proceedings of the ... Workshop on Patient-Oriented Language Processing · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Investigating Substance Use via Reddit: Systematic Scoping Review.Journal of medical Internet research · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abeed SarkerDepartment of Biomedical Informatics, School of Medicine, Emory University, GA, 30322, Atlanta, Georgia. abeed@dbmi.emory.edu.
Nisha NatarajNational Center for Injury Prevention and Control, Centers for Disease Control and Prevention, GA, 30341, Atlanta, Georgia.
Wesley SiuRollins School of Public Health, Emory University, GA, 30322, Atlanta, Georgia.
Sabrina LiDepartment of Computer Science, Emory University, GA, 30322, Atlanta, Georgia.
Christopher M JonesNational Center for Injury Prevention and Control, Centers for Disease Control and Prevention, GA, 30341, Atlanta, Georgia.
Steven A SumnerNational Center for Injury Prevention and Control, Centers for Disease Control and Prevention, GA, 30341, Atlanta, Georgia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTimely data from official sources regarding the impact of the COVID-19 pandemic on people who use prescription and illegal opioids is lacking. We conducted a large-scale, natural language processing (NLP) analysis of conversations on opioid-related drug forums to better understand concerns among people who use opioids.

methodsIn this retrospective observational study, we analyzed posts from 14 opioid-related forums on the social network Reddit. We applied NLP to identify frequently mentioned substances and phrases, and grouped the phrases manually based on their contents into three broad key themes: (i) prescription and/or illegal opioid use; (ii) substance use disorder treatment access and care; and (iii) withdrawal. Phrases that were unmappable to any particular theme were discarded. We computed the frequencies of substance and theme mentions, and quantified their volumes over time. We compared changes in post volumes by key themes and substances between pre-COVID-19 (1/1/2019-2/29/2020) and COVID-19 (3/1/2020-11/30/2020) periods.

resultsSeventy-seven thousand six hundred fifty-two and 119,168 posts were collected for the pre-COVID-19 and COVID-19 periods, respectively. By theme, posts about treatment and access to care increased by 300%, from 0.631 to 2.526 per 1000 posts between the pre-COVID-19 and COVID-19 periods. Conversations about withdrawal increased by 812% between the same periods (0.026 to 0.235 per 1,000 posts). Posts about drug use did not increase (0.219 to 0.218 per 1,000 posts). By substance, among medications for opioid use disorder, methadone had the largest increase in conversations (20.751 to 56.313 per 1,000 posts; 171.4% increase). Among other medications, posts about diphenhydramine exhibited the largest increase (0.341 to 0.927 per 1,000 posts; 171.8% increase).

conclusionsConversations on opioid-related forums among people who use opioids revealed increased concerns about treatment and access to care along with withdrawal following the emergence of COVID-19. Greater attention to social media data may help inform timely responses to the needs of people who use opioids during COVID-19.

Indexed as

COVID-19Opioid-Related DisordersSocial MediaAnalgesics, OpioidHumansNatural Language ProcessingPandemicsSARS-CoV-2Analgesics, OpioidCoronavirus (MeSH ID: D017934)COVID-19 (MeSH ID: D000086382)Natural language processing (MeSH ID: D009323)Opioids (MeSH ID: D000701)Opioid use disorder (MeSH ID: D009293)Social media (MeSH ID: D061108)Text mining (MeSH ID: D057225)

Identifiers

PMID35248103
PMCPMC8897722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.