Evidence map›Paper›PMID 35248055›Full record

ArticleMalaria journal2022

Implementation of community case management of malaria in malaria endemic counties of western Kenya: are community health volunteers up to the task in diagnosing malaria?

Enock Marita, Bernard Langat, Teresa Kinyari, Patrick Igunza, Donald Apat, Josephat Kimori, Jane Carter, Richard Kiplimo, Samuel Muhula

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Enock MaritaAmref Health Africa, P. O. Box 30125, Nairobi, 00100, Kenya. enockmarita@gmail.com.ORCID http://orcid.org/0000-0001-7923-1271
Bernard LangatAmref Health Africa, P. O. Box 30125, Nairobi, 00100, Kenya.
Teresa KinyariUniversity of Nairobi, P.O Box 30197, Nairobi, 00100, Kenya.
Patrick IgunzaAmref Health Africa, P. O. Box 30125, Nairobi, 00100, Kenya.
Donald ApatAmref Health Africa, P. O. Box 30125, Nairobi, 00100, Kenya.
Josephat KimoriAmref Health Africa, P. O. Box 30125, Nairobi, 00100, Kenya.
Jane CarterAmref Health Africa, P. O. Box 30125, Nairobi, 00100, Kenya.
Richard KiplimoNational Tuberculosis, Leprosy and Lung Disease Programme, P.O. Box 20781, Nairobi, Kenya.
Samuel MuhulaAmref Health Africa, P. O. Box 30125, Nairobi, 00100, Kenya.
Amref Health Africa · KEUniversity of Nairobi · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCommunity case management of malaria (CCMm) is an equity-focused strategy that complements and extends the reach of health services by providing timely and effective management of malaria to populations with limited access to facility-based healthcare. In Kenya, CCMm involves the use of malaria rapid diagnostic tests (RDT) and treatment of confirmed uncomplicated malaria cases with artemether lumefantrine (AL) by community health volunteers (CHVs). The test positivity rate (TPR) from CCMm reports collected by the Ministry of Health in 2018 was two-fold compared to facility-based reports for the same period. This necessitated the need to evaluate the performance of CHVs in conducting malaria RDTs.

methodsThe study was conducted in four counties within the malaria-endemic lake zone in Kenya with a malaria prevalence in 2018 of 27%; the national prevalence of malaria was 8%. Multi-stage cluster sampling and random selection were used. Results from 200 malaria RDTs performed by CHVs were compared with test results obtained by experienced medical laboratory technicians (MLT) performing the same test under the same conditions. Blood slides prepared by the MLTs were examined microscopically as a back-up check of the results. A Kappa score was calculated to assess level of agreement. Sensitivity, specificity, and positive and negative predictive values were calculated to determine diagnostic accuracy.

resultsThe median age of CHVs was 46 (IQR: 38, 52) with a range (26-73) years. Females were 72% of the CHVs. Test positivity rates were 42% and 41% for MLTs and CHVs respectively. The kappa score was 0.89, indicating an almost perfect agreement in RDT results between CHVs and MLTs. The overall sensitivity and specificity between the CHVs and MLTs were 95.0% (95% CI 87.7, 98.6) and 94.0% (95% CI 88.0, 97.5), respectively.

conclusionEngaging CHVs to diagnose malaria cases under the CCMm strategy yielded results which compared well with the results of qualified experienced laboratory personnel. CHVs can reliably continue to offer malaria diagnosis using RDTs in the community setting.

Indexed as

AntimalarialsMalariaAdultAgedArtemetherArtemether, Lumefantrine Drug CombinationCase ManagementCommunity Health WorkersDiagnostic Tests, RoutineFemaleHumansKenyaMiddle AgedPublic HealthVolunteersAntimalarialsArtemetherArtemether, Lumefantrine Drug CombinationCommunity case management of malariaCommunity health volunteersRapid diagnostic testTest positivity rate

Identifiers

PMID35248055
PMCPMC8897909
OpenAlexW4220755819

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.