Evidence map›Paper›PMID 35247684›Full record

ArticleJournal of biomechanics2022

Femoral version deformities alter joint reaction forces in dysplastic hips during gait.

Molly C Shepherd, Brecca M M Gaffney, Ke Song, John C Clohisy, Jeffrey J Nepple, Michael D Harris

Open access · greenAbstract read
In one paragraph

Article in Journal of biomechanics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Does Deformity Severity Dictate Which Side Initially Develops Symptoms in Bilaterally Dysplastic Hips?Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Molly C ShepherdProgram in Physical Therapy, Washington University School of Medicine, St. Louis, MO, USA.
Brecca M M GaffneyDepartment of Mechanical Engineering, University of Colorado-Denver, Denver, CO, USA.
Ke SongDepartment of Mechanical Engineering and Materials Science, Washington University in St. Louis, St. Louis, MO, USA.
John C ClohisyDepartment of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Jeffrey J NeppleDepartment of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Michael D HarrisProgram in Physical Therapy, Washington University School of Medicine, St. Louis, MO, USA; Department of Mechanical Engineering and Materials Science, Washington University in St. Louis, St. Louis, MO, USA; Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: harrismi@wustl.edu.
Washington University in St. Louis · USUniversity of Colorado Denver · US

Funding

Resource Based Center for Musculoskeletal Biology and Medicine (Overall Application)P30AR074992 · NIAMS · WASHINGTON UNIVERSITY · PI MATTHEW J SILVA · 2019 to 2026
$6.8M
DOCTORAL TRAINING PROGRAM IN MOVEMENT SCIENCET32HD007434 · NICHD · WASHINGTON UNIVERSITY · PI Michael D Harris, Catherine Lang · 1993 to 2026
$4.2M
Muscle Geometry and its Influence on Function in Patients with Developmental Dysplasia of the HipK01AR072072 · NIAMS · WASHINGTON UNIVERSITY · PI HARRIS, MICHAEL D · 2018 to 2022
$554k
Effects of Simulated Interventions on Hip Articular Cartilage Loading in Patients with Femoroacetabular Impingement and Developmental Dysplasia of the HipF32AR075349 · NIAMS · WASHINGTON UNIVERSITY · PI GAFFNEY, BRECCA · 2019 to 2020
$97k
NIAMS NIH HHS F32 AR075349NIAMS NIH HHS K01 AR072072NIAMS NIH HHS P30 AR074992NICHD NIH HHS T32 HD007434
6 · The paper itself

Abstract

Developmental dysplasia of the hip (DDH) causes hip instability and early-onset osteoarthritis. The focus on pathomechanics in DDH has centered on the shallow acetabulum, however there is growing awareness of the role of femoral deformities in joint damage. The objective of this study was to determine the influence of femoral version (FV) on the muscle and joint reaction forces (JRFs) of dysplastic hips during gait. Magnetic resonance images, in-vivo gait data, and musculoskeletal models were used to calculate JRFs and simulate changes due to varying FV deformities. Rotation about the long axis of the femur was added in the musculoskeletal models to simulate FV values from -5° (relative retroversion) to + 35° (increased anteversion). In our simulations, FV deformities caused the largest changes to the anteroposterior and resultant JRFs. From a normal FV of 15°, a 15° increase in femoral anteversion caused JRFs to be less posterior in early stance (Δ = 0.43 ± 0.22 xbodyweight) and more anterior in late stance (Δ = 0.60 ± 14 xbodyweight). Relative retroversion caused anteroposterior changes that were similar to anteversion in early stance but opposite in late stance. Resultant JRFs experienced the largest changes during late stance where anteversion raised the peak by 0.48 ± 0.15 xbodyweight and relative retroversion lowered the peak by 0.32 ± 0.30 xbodyweight. Increasing anteversion increased hip flexor and abductor muscle forces, which caused the changes in JRFs. Identifying how FV deformities influence hip joint loading can elucidate their role in the mechanisms of hip degeneration in patients with DDH.

Indexed as

AcetabulumBiomechanical PhenomenaFemurGaitHip DislocationHip JointHumansMagnetic Resonance ImagingOsteoarthritis, HipRetrospective StudiesDevelopmental dysplasia of the hipFemoral versionGaitJoint reaction forcesMusculoskeletal modeling

Identifiers

PMID35247684
PMCPMC9064981
OpenAlexW4214777337

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.