ArticlePlant biotechnology journal2022
Integrated multi-omic data and analyses reveal the pathways underlying key ornamental traits in carnation flowers.
Article in Plant biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Multi-omics time-series analysis in microbiome research: a systematic review.Briefings in bioinformatics · 2025Pooled it
- Genomic basis of scent loss and functional divergence in wild and cultivated carnations (Horticulture research · 2026Article
- miR172-Mediated Repression ofInternational journal of molecular sciences · 2026Article
- Development of KASP Markers for Carnation Germplasm (or Cultivar) Fingerprinting Based on Reduced-Representation Genome Sequencing Technology.Plants (Basel, Switzerland) · 2026Article
- Multi-Omics Analysis Provides Insights into Developmental Tepal Coloration inPlants (Basel, Switzerland) · 2026Article
- Integrative multi-omics analysis reveals the genetic architecture of floral traits inHorticulture research · 2026Article
- Assembling the chromosome-level genome of Arctium Lappa L. provides new insights into carotenoid biosynthesis.BMC plant biology · 2025Article
- Studies on the mother flower carnation: past, present, and future.Horticulture research · 2025Article
- The chromosome-level genome of Hemerocallis middendorffii provides new insights into the floral scents and color biosynthesis in Chinese native daylily.BMC plant biology · 2025Article
- Advancing ornamental plant breeding through genomic technologies: opportunities, challenges, and future directions.Functional & integrative genomics · 2025Review
- Transcriptome Analysis Reveals Association of E-Class AmMADS-Box Genes with Petal Malformation inInternational journal of molecular sciences · 2025Article
- Chromosome-level genome assembly assisting for dissecting mechanism of anthocyanin regulation in kiwifruit (Actinidia arguta).Molecular horticulture · 2025Article
- Integrative Omics Analysis Reveals Mechanisms of Anthocyanin Biosynthesis in Djulis Spikes.Plants (Basel, Switzerland) · 2025Article
- Genetic architecture and genomic prediction of vase life in carnation.Frontiers in plant science · 2025Article
- Integrated metabolite profiling and transcriptome analysis identify candidate genes involved in diterpenoid alkaloid biosynthesis inFrontiers in plant science · 2025Article
- A high-quality haplotype genome of Michelia alba DC reveals differences in methylation patterns and flower characteristics.Molecular horticulture · 2024Article
- Haplotype-resolved genome assembly of the diploid Rosa chinensis provides insight into the mechanisms underlying key ornamental traits.Molecular horticulture · 2024Article
- Integration of Metabolomic and Transcriptomic Analyses Reveals the Molecular Mechanisms of Flower Color Formation inPlants (Basel, Switzerland) · 2024Article
- The haplotype-resolved telomere-to-telomere carnation (Horticulture research · 2024Article
- Multi-integrated genomic data for Passiflora foetida provides insights into genome size evolution and floral development in Passiflora.Molecular horticulture · 2023Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carnation (Dianthus caryophyllus) is one of the most popular ornamental flowers in the world. Although numerous studies on carnations exist, the underlying mechanisms of flower color, fragrance, and the formation of double flowers remain unknown. Here, we employed an integrated multi-omics approach to elucidate the genetic and biochemical pathways underlying the most important ornamental features of carnation flowers. First, we assembled a high-quality chromosome-scale genome (636 Mb with contig N50 as 14.67 Mb) of D. caryophyllus, the 'Scarlet Queen'. Next, a series of metabolomic datasets was generated with a variety of instrumentation types from different parts of the flower at multiple stages of development to assess spatial and temporal differences in the accumulation of pigment and volatile compounds. Finally, transcriptomic data were generated to link genomic, biochemical, and morphological patterns to propose a set of pathways by which ornamental traits such as petal coloration, double flowers, and fragrance production are formed. Among them, the transcription factors bHLHs, MYBs, and a WRKY44 homolog are proposed to be important in controlling petal color patterning and genes such as coniferyl alcohol acetyltransferase and eugenol synthase are involved in the synthesis of eugenol. The integrated dataset of genomics, transcriptomics, and metabolomics presented herein provides an important foundation for understanding the underlying pathways of flower development and coloration, which in turn can be used for selective breeding and gene editing for the development of novel carnation cultivars.
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