ArticleJournal of nephrology2022
Pre-dialysis diastolic blood pressure and intradialytic hypotension in patients undergoing maintenance haemodialysis.
Article in Journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 3 citations in OpenAlex.
- The value of pleth variability index in predicting hypotension during maintenance hemodialysis: a prospective observational multicenter study (PVi-HD study).BMC nephrology · 2026Observational
- Effects of infant touch on the growth and neurodevelopment of preterm infants.Pakistan journal of medical sciences · 2026Article
- The association of anxiety, depression, sleep quality and intradialytic hypotension in hemodialysis patients: a cross-sectional study.Frontiers in psychiatry · 2026Article
- Intradialytic hypotension and worse outcomes in patients with acute kidney injury requiring intermittent hemodialysis.Kidney research and clinical practice · 2026Article
- Association between intradialytic hypotension and physical function in patients undergoing maintenance hemodialysis: a multicenter cross-sectional study.Frontiers in medicine · 2025Article
- Effect of periodic nursing interventions on improving compliance behavior and health status in long-term Hemodialysis patients.Pakistan journal of medical sciences · 2024Article
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Authors and funding
3 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundIntradialytic hypotension is a clinically relevant complication in haemodialysis patients. Pre-dialysis diastolic blood pressure is routinely measured. However, the association between pre-dialysis diastolic blood pressure and intradialytic hypotension is not well understood.
methodsPatient-level (N = 545) and haemodialysis session-level (N = 3261) data were collected; the exposure variable was pre-dialysis diastolic blood pressure. The primary outcome of interest was the development of intradialytic hypotension, defined as any nadir < 100 mmHg if the pre-dialysis systolic blood pressure was ≥ 160 mmHg, or any nadir < 90 mmHg if the pre-dialysis systolic blood pressure was < 160 mmHg. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated using mixed-effects logistic regression for the association between pre-dialysis diastolic blood pressure and intradialytic hypotension, after adjusting for potential confounders.
resultsIntradialytic hypotension occurred in 14.4% of the sessions. All sessions were divided into five categories according to pre-dialysis diastolic blood pressure. The adjusted ORs for intradialytic hypotension were 2.72 (95% CI 1.64-4.51), 1.07 (95% CI 0.68-1.66), 1.68 (95% CI 1.08-2.62), and 1.81 (95% CI 1.05-3.14) in sessions with pre-dialysis diastolic blood pressure of < 60 mmHg, ≥ 60 to < 70 mmHg, ≥ 80 to < 90 mmHg, and ≥ 90 mmHg, respectively, compared with the reference pre-dialysis diastolic blood pressure of ≥ 70 to < 80 mmHg. Cubic spline analyses revealed a reverse J-shaped association between pre-dialysis diastolic blood pressure and intradialytic hypotension.
conclusionsLow and high pre-dialysis diastolic blood pressure levels were associated with intradialytic hypotension. This may help identify patients at a high risk of developing intradialytic hypotension.
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