Evidence map›Paper›PMID 35247140›Full record

ArticleMolecular neurobiology2022

Activation of the GPX4/TLR4 Signaling Pathway Participates in the Alleviation of Selenium Yeast on Deltamethrin-Provoked Cerebrum Injury in Quails.

Jiayi Li, Zhongxian Yu, Bing Han, Siyu Li, Yueying Lv, Xiaoqiao Wang, Qingyue Yang, Pengfei Wu, Yuge Liao, Bing Qu and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jiayi LiCollege of Veterinary Medicine, Northeast Agricultural University, 600 Changjiang Road, Harbin, 150030, China.
Zhongxian YuPharmacy Department, The Affiliated Hospital To Changchun University of Chinese Medicine, 1478 Gongnong Road, Hongqi Street, Chaoyang District, Changchun, Jilin Province, 130021, China.
Bing HanCollege of Veterinary Medicine, Northeast Agricultural University, 600 Changjiang Road, Harbin, 150030, China.
Siyu LiCollege of Veterinary Medicine, Northeast Agricultural University, 600 Changjiang Road, Harbin, 150030, China.
Yueying LvCollege of Veterinary Medicine, Northeast Agricultural University, 600 Changjiang Road, Harbin, 150030, China.
Xiaoqiao WangCollege of Veterinary Medicine, Northeast Agricultural University, 600 Changjiang Road, Harbin, 150030, China.
Qingyue YangCollege of Veterinary Medicine, Northeast Agricultural University, 600 Changjiang Road, Harbin, 150030, China.
Pengfei WuCollege of Veterinary Medicine, Northeast Agricultural University, 600 Changjiang Road, Harbin, 150030, China.
Yuge LiaoCollege of Veterinary Medicine, Northeast Agricultural University, 600 Changjiang Road, Harbin, 150030, China.
Bing QuCollege of Veterinary Medicine, Northeast Agricultural University, 600 Changjiang Road, Harbin, 150030, China.
Zhigang ZhangCollege of Veterinary Medicine, Northeast Agricultural University, 600 Changjiang Road, Harbin, 150030, China. zhangzhigang@neau.edu.cn.ORCID http://orcid.org/0000-0002-4974-5850
Northeast Agricultural University · CNThe Affiliated Hospital to Changchun University of Chinese Medicine · CN

Funding

National Natural Science Foundation of China 31972754Scientific Research Foundation for the Returned Overseas Chinese Scholars of Heilongjiang Province LC2017007
6 · The paper itself

Abstract

Deltamethrin (DLM) is a member of pyrethroid pesticide widely applied for agriculture and aquaculture, and its residue in the environment seriously threatens the bio-safety. The cerebrum might be vulnerable to pesticide-triggered oxidative stress. However, there is no specific antidote for treating DLM-triggered cerebral injury. Selenium (Se) is an essential trace element functionally forming selenoprotein glutathione peroxidase (GPX) in antioxidant defense. Se yeast (SY) is a common and effective organic form of Se supplement with high selenomethionine content. Accordingly, this study focused on investigating the therapeutic potential of SY on DLM-induced cerebral injury in quails after chronically exposing to DLM and exploring the underlying mechanisms. Quails were treated with/without SY (0.4 mg kg

Indexed as

CerebrumPesticidesSeleniumAnimalsAntioxidantsNitrilesPyrethrinsQuailSaccharomyces cerevisiaeSignal TransductionToll-Like Receptor 4AntioxidantsdecamethrinNitrilesPesticidesPyrethrinsSeleniumToll-Like Receptor 4ApoptosisCerebrum injuryDeltamethrinGPX4/TLR4Oxidative stressSelenium yeast

Identifiers

PMID35247140
OpenAlexW4220848769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.