ArticleArchives of osteoporosis2022
The pattern and trends of disease burden due to low bone mineral density from 1990 to 2019 in China: findings from the Global Burden of Disease Study 2019.
Article in Archives of osteoporosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- The efficacy and safety of Epimedium in the treatment of primary osteoporosis: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- The recent progression of extracellular vesicles application in osteoporosis.Frontiers in pharmacology · 2026Review
- Role and Validation of Lactylation-Related Gene Markers in Postmenopausal Osteoporosis.Applied biochemistry and biotechnology · 2025Article
- [Epidemiological survey of osteoporosis in Beijing over the past decade: a single-center analysis of dual-energy X-ray absorptiometry scans from 30 599 individuals].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- The incidence, prevalence, and health burden of hip fractures in China: Data from the global burden of disease study 2019.Preventive medicine reports · 2024Article
- Adherence to the dietary approaches to stop hypertension and bone health in the Chinese elderly.Journal of bone and mineral metabolism · 2023Article
- Identification of key immune genes of osteoporosis based on bioinformatics and machine learning.Frontiers in endocrinology · 2023Article
- Bibliometric and visualized analysis of exercise and osteoporosis from 2002 to 2021.Frontiers in medicine · 2022Article
- Risk of fracture following gastric surgery for benign and malignant conditions: A study level pooled analysis of population-based cohort studies.Frontiers in oncology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoporosis is becoming increasing important health problem in China. This study shows that the disease burden of low bone mineral density (BMD) in China is large and will remain increasing with the growth of aging population. In addition, male low BMD should not be ignored. Although burden of low BMD is partially representative of the real burden of osteoporosis, the information provided in our study could be used to better inform targeted public health prevention and management programs for osteopososis. PURPOSE: We aim to investigate the pattern and trends of disease burden due to low BMD by gender, year, and age in China from 1990 to 2019.
methodsData on summary exposure value (SEV) and disability-adjusted life years (DALYs) due to low BMD was obtained from the Global Burden of Disease Study 2019, and analyzed by gender, age, and years. Average annual percent change (AAPC) and annual percent change (APC) were calculated to qualify the trends of burden due to low BMD.
resultIn 2019, the age-standardized SEV was higher in females than that in males (23.04, 95% UI = [17.25-29.83] and 12.50, 95% UI = [7.71-19.25], respectively), while the total number of DALYs was higher in males than females with 1,698,705.92 (95% UI = 1,281,580.79 to 2,076,364.25) and 1,621,569 (95% UI = 1,266,284.89 to 2,016,399.16), respectively. Though SEV exhibited decreasing trends during 1990 to 2019 in both sexes, the absolute number of DALYs due to low BMD increased steadily and almost doubled in 2019 compared to that in 1990.
conclusionThe burden of low BMD remains large and continues to increase. Although females are prone to low BMD, the disease burden for males should not be ignored.
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