Evidence map›Paper›PMID 35247077›Full record

ArticleMikrochimica acta2022

Cellulose-based hydrogel on quantum dots with molecularly imprinted polymers for the detection of CA19-9 protein cancer biomarker.

Ana Margarida L Piloto, David S M Ribeiro, S Sofia M Rodrigues, João L M Santos, Paula Sampaio, Maria Goreti Ferreira Sales

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 44 citations in OpenAlex.

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  6. Ultrasensitive photoelectrochemical immunosensor based on floral cluster SnSFrontiers in bioengineering and biotechnology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ana Margarida L PilotoBioMark/ISEP, School of Engineering of the Polytechnic Institute of Porto, Porto, Portugal. amlpc@isep.ipp.pt.
David S M RibeiroLAQV, REQUIMTE, Faculty of Pharmacy, Laboratory of Applied Chemistry, Department of Chemical Sciences, University of Porto, Porto, Portugal.
S Sofia M RodriguesLAQV, REQUIMTE, Faculty of Pharmacy, Laboratory of Applied Chemistry, Department of Chemical Sciences, University of Porto, Porto, Portugal.
João L M SantosLAQV, REQUIMTE, Faculty of Pharmacy, Laboratory of Applied Chemistry, Department of Chemical Sciences, University of Porto, Porto, Portugal.
Paula Sampaioi3S - Instituto de Investigação e Inovação em Saúde, Universidade Do Porto, Porto, Portugal.
Maria Goreti Ferreira SalesBioMark/ISEP, School of Engineering of the Polytechnic Institute of Porto, Porto, Portugal.
Rede de Química e Tecnologia · PTInstituto de Biologia Molecular e CelularPolytechnic Institute of Porto · PTUniversity of Coimbra · PT

Funding

European Commission PPBI-POCI-01-0145-FEDER-022122Fundação para a Ciência e a Tecnologia Program DL 57/2016 Norma transitória.Fundação para a Ciência e a Tecnologia Project 3C´s (PTDC/AAG TEC/5400/2014).Fundação para a Ciência e a Tecnologia SFRH/BPD/116067/2016
6 · The paper itself

Abstract

Molecularly imprinted polymers MIPs were successfully assembled around quantum dots (QDs), for the detection of the protein biomarker CA19-9 associated to pancreatic cancer (PC). These imprinted materials MIP@QDs were incorporated within the cellulose hydrogel with retention of its conformational structure inside the binding cavities. The concept is to use MIPs which function as the biorecognition elements, conjugated to cadmium telluride QDs as the sensing system. The excitation wavelength was set to 477 nm and the fluorescence signal was measured at its maximum intensity, with an emission range between 530 and 780 nm. The fluorescence quenching of the imprinted cellulose hydrogels occurred with increasing concentrations of CA19-9, showing linearity in the range 2.76 × 10

Indexed as

Molecular ImprintingNeoplasmsQuantum DotsBiomarkers, TumorCA-19-9 AntigenCelluloseHumansHydrogelsMolecularly Imprinted PolymersBiomarkers, TumorCA-19-9 AntigenCelluloseHydrogelsMolecularly Imprinted PolymersCA 19–9 proteinImprinted cellulose hydrogelsMolecularly imprinted polymersOptical sensorPancreatic cancer diagnosisQuantum dots

Identifiers

PMID35247077
OpenAlexW4220906072

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.