Evidence map›Paper›PMID 35247059›Full record

ArticleSocial psychiatry and psychiatric epidemiology2022

An ecological study of temporal trends in 'deaths of despair' in England and Wales.

Elizabeth Augarde, David Gunnell, Becky Mars, Matthew Hickman

Open access · hybridAbstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

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  13. Premature deaths have many names.Social psychiatry and psychiatric epidemiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Elizabeth AugardePopulation Health Sciences, University of Bristol, Bristol, UK. elizabeth.augarde@dhsc.gov.uk.ORCID http://orcid.org/0000-0003-2216-720X
David GunnellPopulation Health Sciences, University of Bristol, Bristol, UK.
Becky MarsPopulation Health Sciences, University of Bristol, Bristol, UK.
Matthew HickmanPopulation Health Sciences, University of Bristol, Bristol, UK.
University of Bristol · GBDepartment of Health and Social Care · GBUniversity Hospitals Bristol NHS Foundation Trust · GB

Funding

Medical Research Council MR/N00616X/1
6 · The paper itself

Abstract

purposeThere is growing interest in the concept of 'deaths of despair' (DoD)-defined as deaths from three causes: suicide, drug poisoning, and alcohol-related conditions-as a more comprehensive indicator of the impact of psychological distress on mortality. The purpose of this study is to investigate the degree of commonality in trends and geographic patterning of deaths from these causes in England and Wales.

methodsWHO mortality data were used to calculate age-standardised, sex-specific temporal trends in DoD mortality and in mortality from suicide, drug poisonings, and alcohol-related conditions in England and Wales, 2001-2016. Three-year average crude rates were calculated for English local authorities for 2016-2018 and associations between rates were assessed using Spearman's rank correlation.

resultsBetween 2001 and 2016, the DoD mortality rate increased by 21·6% (males) and 16·9% (females). The increase was largely due to a rise in drug poisoning deaths, with limited tracking between trends in mortality by each cause. DoD mortality risk was highest in middle-aged people; there were rises in all age groups except 15-24 year old males and 65 + females. There were strong positive correlations (r = 0.66(males) and 0.60(females)) between local authority-area drug poisoning and alcohol-specific mortality rates in 2016-2018. Correlations of these outcomes with suicide were weaker (r = 0.29-0.54).

conclusionsDoD mortality is increasing in England and Wales but there is limited evidence of commonality in the epidemiology of cause-specific mortality from the component causes of DoD (suicide, drug poisoning and alcohol-related conditions), indicating the need for tailored prevention for each outcome.

Indexed as

SuicideAdolescentAdultAgedEnglandFemaleHumansMaleMiddle AgedWalesYoung AdultAlcohol consumptionDrug useEpidemiologyMental healthMortalitySuicide

Identifiers

PMID35247059
PMCPMC9090864
OpenAlexW4221125814

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.