Evidence map›Paper›PMID 35247021›Full record

ReviewPharmacoepidemiology and drug safety2022

Evaluating opioid analgesic prescribing limits: A narrative review.

Amy E Seitz, Karen A Janiszewski, Gery P Guy, Ryan T Tapscott, Emily B Einstein, Tamra E Meyer, Jessica Tierney, Judy Staffa, Christopher M Jones, Wilson M Compton

Abstract readReview
In one paragraph

Review in Pharmacoepidemiology and drug safety, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amy E SeitzCenter for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
Karen A JaniszewskiCenter for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
Gery P GuyNational Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Ryan T TapscottNational Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Emily B EinsteinNational Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland, USA.
Tamra E MeyerCenter for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
Jessica TierneyCenter for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
Judy StaffaCenter for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
Christopher M JonesNational Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Wilson M ComptonNational Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

purposeIn response to the opioid crisis, opioid analgesic guidelines and prescribing limits have proliferated. The purpose of this narrative review is to examine evidence from studies evaluating the patient or public health impact of federal and state opioid analgesic prescribing guidelines and laws, describe gaps and challenges in current research, and highlight opportunities for improving future research.

methodsWe focused on evidence from a literature review covering 2013 through 2019. We identified 30 studies evaluating opioid analgesic thresholds based on federal policies and guidelines, state laws, and Medicaid state plans that attempt to influence the course of patient care at or when the limit is exceeded (e.g., prior authorization).

resultsMost studies evaluated changes in prescribing or dispensing patterns of opioid analgesics, largely finding decreases in prescribing after policy enactment. Fewer studies evaluated patient or public health outcomes beyond changes in prescribing and dispensing patterns; results were infrequently stratified by potentially important sociodemographic and clinical factors. No studies assessed the potential for adverse patient outcomes for which we have emerging evidence of harms.

conclusionsWe describe knowledge gaps and propose opportunities for future research to sufficiently assess the potential impact and unintended consequences of opioid analgesic prescribing laws, regulations, guidelines, and policies.

Indexed as

Analgesics, OpioidPractice Patterns, Physicians'HumansMedicaidOpioid EpidemicPolicyUnited StatesAnalgesics, Opioidopioid analgesicprescribing limit

Identifiers

PMID35247021
PMCPMC9078148

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.