SynthesisReviews in medical virology2022
COVID-19 outcomes in paediatric cancer: A large scale pooled meta-analysis of 984 cancer patients.
Synthesis in Reviews in medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Meta-analysis of mortality factors after COVID-19 infection in pediatric oncology patients.Frontiers in oncology · 2025Pooled it
- Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis.Journal of the Pediatric Infectious Diseases Society · 2024Pooled it
- Evidence linking COVID-19 and the health/well-being of children and adolescents: an umbrella review.BMC medicine · 2024Pooled it
- COVID-19 outcomes in paediatric cancer: A large scale pooled meta-analysis of 984 cancer patients.Reviews in medical virology · 2022Pooled it
- Global, regional, and national burden for childhood and adolescent cancers from 1990 to 2021: from the Global Burden of Disease Study 2021.Pediatric surgery international · 2025Article
- Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis.medRxiv : the preprint server for health sciences · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to study the outcomes of COVID-19 in paediatric cancer patients. On 26 October 2021, we did a systematic search for relevant articles in seven electronic databases followed by manual search. We included cancer patients aged ≤18 years. Event rates and the 95% confidence interval (95%CI) were used to report the results. We included 21 papers after screening of 2759 records. The pooled rates of hospitalisation, intensive care unit (ICU) admission and mortality were 44% (95%CI: 30-59), 14% (95%CI: 9-21) and 9% (95%CI: 6-12), respectively. Moreover, subgroup analysis revealed that high income countries had better COVID-19 outcomes compared to upper middle income countries and lower middle income countries in terms of hospitalisation 30% (95%CI: 17-46), 60% (95%CI: 29-84) and 47% (95%CI: 36-58), ICU admission 7% (95%CI: 1-32), 13% (95%CI: 7-23) and 18% (95%CI: 6-41), and mortality 3% (95%CI: 2-5), 12% (95%CI: 8-18) and 13% (95%CI: 8-20), in order. In general, absence of specific pharmacologic intervention to prevent infection with the scarcity of vaccination coverage data among paediatric groups and its impact, high priority caution is required to avoid SARS-CoV-2 infection among paediatric cancer patients. Furthermore, our results highlight the importance of promoting care facilities for this vulnerable population in low and middle income regions to ensure quality care among cancer patients during pandemic crisis.
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