Evidence map›Paper›PMID 35246665›Full record

ArticleEuropean journal of human genetics : EJHG2022

Human mitochondrial RNA modifications associate with tissue-specific changes in gene expression, and are affected by sunlight and UV exposure.

Tal Cohen, Hadar Medini, Chen Mordechai, Alal Eran, Dan Mishmar

Open access · bronzeAbstract read
In one paragraph

Article in European journal of human genetics : EJHG, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tal CohenDepartment of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, 8410501, Israel.
Hadar MediniDepartment of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, 8410501, Israel.
Chen MordechaiDepartment of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, 8410501, Israel.
Alal EranDepartment of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, 8410501, Israel.
Dan MishmarDepartment of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, 8410501, Israel. dmishmar@bgu.ac.il.ORCID http://orcid.org/0000-0003-3488-8792
Ben-Gurion University of the Negev · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA-DNA differences (RDD) have previously been identified in the human mitochondrial RNA (mt-RNA) transcripts, yet their functional impact is poorly understood. By analyzing 4928 RNA-seq samples from 23 body sites, we found that mtDNA gene expression negatively correlated with the levels of both m

Indexed as

DNA, MitochondrialSunlightGene ExpressionHumansRNARNA, MitochondrialDNA, MitochondrialRNARNA, Mitochondrial

Identifiers

PMID35246665
PMCPMC9712611
OpenAlexW4214894041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.