Evidence map›Paper›PMID 35246404›Full record

Trial reportJournal of geriatric oncology2022

Cancer and aging: Reflections for elders- Expressive writing intervention: A pilot study.

Rebecca C Tutino, Rebecca M Saracino, Judith Kelman, Elizabeth A Schofield, Andrew J Roth, Christian J Nelson

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of geriatric oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00984321 (A Pilot Study of Geriatric Specific Interventions for Quality of Life in Elderly Patients With Cancer), which is not on this map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00984321 nacompletednot on this map

A Pilot Study of Geriatric Specific Interventions for Quality of Life in Elderly Patients With Cancer

TypeinterventionalSponsorMemorial Sloan Kettering Cancer CenterRan2009 to 2025Enrolled107ConditionsBreast Cancer, Prostate Cancer, Lung Cancer, Lymphoma CancerArmsgroup intervention and questionnaires, individual phone intervention and questionnaires, expressive writing (arm will not be include in the randomization)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Systematic review and meta-analysis of the effectiveness of expressive writing disclosure on cancer and palliative care patients' health-related outcomes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  3. Trial
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rebecca C TutinoDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Avenue, New York, NY, United States; Fordham University, 441 East Fordham Road, Dealy 226, Bronx, NY, United States. Electronic address: tutinorebecca@gmail.com.
Rebecca M SaracinoDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Avenue, New York, NY, United States.
Judith KelmanDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Avenue, New York, NY, United States.
Elizabeth A SchofieldDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Avenue, New York, NY, United States.
Andrew J RothDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Avenue, New York, NY, United States.
Christian J NelsonDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Avenue, New York, NY, United States.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Psychosocial Palliative & Community Research in CancerT32CA009461 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI JENNIFER L HAY, Jamie S. Ostroff · 1985 to 2026
$10.1M
Behavioral Activation for Depression in Older Adult Cancer Survivors: Pilot Randomized Control Trial and Implementation OutcomesK08CA252633 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI SARACINO, REBECCA · 2021 to 2025
$902k
NCI NIH HHS K08 CA252633NCI NIH HHS P30 CA008748NCI NIH HHS T32 CA009461
6 · The paper itself

Abstract

objectivesThe Cancer and Aging: Reflections for Elders Expressive Writing Intervention (CARE-Express) was developed to enhance coping and minimize psychological distress in older adults with cancer. The aim of the current study is to evaluate the feasibility and initial efficacy of CARE-Express. MATERIALS AND

methodsSeventy-one distressed older adults (≥70) with cancer were assigned to CARE-Express (n = 41) or the Enhanced Social Work Control (ESWC) arm (n = 30). Participants completed five telephone sessions over seven weeks and were assessed on psychosocial variables at baseline, post-intervention, and four months post study enrollment. Feasibility was assessed by examining rates of eligibility, acceptance, retention, assessment, and fidelity. Initial efficacy was evaluated using standardized effect sizes.

resultsAdequate rates of acceptance (29%), eligibility (66%), retention (90%), assessment (70% at post-intervention, 63% at four month follow-up), and fidelity (97%) were observed. At post-intervention, participants receiving CARE-Express reported less depression compared to ESWC (d = 0.69, p = 0.01) and lower demoralization (d = 0.50, p = 0.06). A small/moderate effect was demonstrated for increased total spirituality scores (d = 0.41, p = 0.07), meaning/peace (d = 0.32, p = 0.20) and faith (d = 0.35, p = 0.07). The CARE-Express group reported greater reductions in behavioral disengagement (d = 0.44, p = 0.06), while ESWC demonstrated a small effect for active coping (d = 0.21, p = 0.31). At four months, differential effects of CARE-Express had attenuated, though small/moderate, effects in favor of CARE-Express remained.

conclusionResults support the feasibility of CARE-Express and its potential positive impact on psychological well-being.

trial registrationRegistered at the US National Institutes of Health (ClinicalTrials.gov) #NCT00984321 on September 25, 2009.

Indexed as

AgingNeoplasmsWritingAdaptation, PsychologicalAgedHumansPilot ProjectsCancerExpressive writingExpressive writing interventionNeoplasmOlder adultsOncologyPhone interventionPsychological distressPsychology

Identifiers

PMID35246404
PMCPMC10108097

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.