ArticleBMC oral health2022
Pulpal and periapical tissue response after direct pulp capping with endosequence root repair material and low-level laser application.
Article in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The trial behind it
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Effect of diode laser pretreatment on dentin thickness and discoloration in deep caries treated with biodentine: a randomized clinical trial.Scientific reports · 2026Trial
- Histological evaluation of pulpal healing following direct pulp capping with polytetrafluoroethylene or melatonin, with or without adjunctive low-level laser therapy in Wistar rat molars.Scientific reports · 2026Article
- Pulp response following direct pulp capping with Tideglusib and mineral trioxide aggregate: an animal study.BMC oral health · 2025Article
- Comparative Analysis of Calcium and Hydroxyl Ion Release from Pulp Dressing Materials in Pulpotomized Premolars.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Article
- The application of lasers in vital pulp therapy: a review of histological effects.Lasers in medical science · 2023Review
- Photobiomodulation Therapy and Pulp-Regenerative Endodontics: A Narrative Review.Bioengineering (Basel, Switzerland) · 2023Review
- Current Applications and Future Directions of Lasers in Endodontics: A Narrative Review.Bioengineering (Basel, Switzerland) · 2023Review
- Physiotherapeutic Protocol and ZnO Nanoparticles: A Combined Novel Treatment Program against Bacterial Pyomyositis.Biology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe study aims to investigate the pulp and periapical reaction and healing after capping with EndoSequence Root Repair Material (ERRM) combined with low-level laser application.
methodsIn 6 rabbits, pulps were exposed via class V, half of the samples received a low-level diode laser at 980 nm. Thereafter, cavities were capped with regular-set ERRM. The specimens were processed for histomorphological examination after 2 weeks and two months.
resultsAfter 2 weeks, images show mild inflammation and organized odontoblasts in lased group. The non-lased group shows more severe inflammation. The predentin thickness was thicker in the lased group with statistical significance (p < 0.05). After 2 months, inflammatory cells were sparse in both lased and non-lased groups. In the periapical area, group one showed dilated blood vessels and thick fibrous connective tissues. In group two, there were more numerous maturations of PDL fibers with scattered inflammatory cells and congested blood vessel.
conclusionsUsing low-level laser therapy in combination with ERRM for pulp capping shortens the inflammatory phase and enhances healing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.