Evidence map›Paper›PMID 35246065›Full record

Observational studyBMC cardiovascular disorders2022

Using HEART2 score to risk stratify chest pain patients in the Emergency Department: an observational study.

Chet D Schrader, Darren Kumar, Yuan Zhou, Stefan Meyering, Nicholas Saltarelli, Naomi Alanis, Chukwuagozie Iloma, Rebecca Smiley, Hao Wang

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. A Closer Look at the HEART Score.Cardiology research · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chet D SchraderDepartment of Emergency Medicine, John Peter Smith Health Network (JPS Health Network), 1500 S. Main St., Fort Worth, TX, 76104, USA.
Darren KumarDepartment of Cardiology, JPS Health Network, 1500 S. Main St., Fort Worth, TX, 76104, USA.
Yuan ZhouDepartment of Industrial, Manufacturing, and Systems Engineering, The University of Texas at Arlington, 701 S. Nedderman Dr., Arlington, TX, 76019, USA.
Stefan MeyeringDepartment of Emergency Medicine, John Peter Smith Health Network (JPS Health Network), 1500 S. Main St., Fort Worth, TX, 76104, USA.
Nicholas SaltarelliDepartment of Emergency Medicine, John Peter Smith Health Network (JPS Health Network), 1500 S. Main St., Fort Worth, TX, 76104, USA.
Naomi AlanisDepartment of Emergency Medicine, John Peter Smith Health Network (JPS Health Network), 1500 S. Main St., Fort Worth, TX, 76104, USA.
Chukwuagozie IlomaDepartment of Emergency Medicine, John Peter Smith Health Network (JPS Health Network), 1500 S. Main St., Fort Worth, TX, 76104, USA.
Rebecca SmileyDepartment of Emergency Medicine, John Peter Smith Health Network (JPS Health Network), 1500 S. Main St., Fort Worth, TX, 76104, USA.
Hao WangDepartment of Emergency Medicine, John Peter Smith Health Network (JPS Health Network), 1500 S. Main St., Fort Worth, TX, 76104, USA. hwang@ies.healthcare.ORCID 0000-0002-5105-0951
John Peter Smith Hospital · USJPS Health Network · USThe University of Texas at Arlington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA significant number of chest pain patients had previous cardiac imaging tests (CIT) performed before being presented to the Emergency Department (ED). The HEART (history, electrocardiogram, age, risk factors, and troponin) score has been used to risk-stratify chest pain patients in the ED, but not particularly for patients with CIT performed. We aim to modify the current HEART score with the addition of most recent CIT findings (referred to as HEART2 score), to predict a 30-day major adverse cardiac event (MACE) among ED chest pain patients, compare the performance accuracy of using HEART versus HEART2 score for 30-day MACE outcome predictions, and further determine the value of HEART2 in a subset group of ED chest pain patients (i.e., ones with previous CIT).

methodsThis is a single-center observational study. We included chest pain patients with HEART scores calculated during their index ED visits. A modified HEART2 score was developed with the addition of CIT findings as one of the HEART2 components. Patients were divided into three groups, including low (≤ 3), moderate (4-6), and high-risk HEART/HEART2 scores (≥ 7). MACE occurrence of a patient with different risks of HEART and HEART2 scores and overall performance accuracy of HEART versus HEART2 score predicting MACE outcomes were compared.

resultsWe included a total of 9419 chest pain patients at ED, among which one out of five patients (1874/9419) had previous CIT performed. Fewer (38.2%) of such patients had low-risk HEART scores in comparison to 55.5% of low-risk HEART2 scores (p < 0.001). The MACE outcomes were similar in low-risk HEART patients compared with low-risk HEART2 patients (2.2% versus 3.1%, p = 0.3021). The overall performance accuracy of using the HEART2 score to stratify chest pain patients with previous CIT was better than using the HEART score's (AUC 0.74 versus 0.71, p = 0.0082).

conclusionsUsing the HEART2 score might be suitable to stratify low-to-moderate risk chest pain patients at ED with a similar 30-days MACE occurrence compared to the HEART score. More importantly, with the use of similar low-risk criteria (HEART2 ≤ 3), over 45% more chest pain patients with previous CIT performed could be discharged directly from ED.

Indexed as

Chest PainEmergency Service, HospitalElectrocardiographyHumansPredictive Value of TestsRisk AssessmentRisk FactorsTroponinTroponinCardiac imaging testChest painEmergency DepartmentMACE

Identifiers

PMID35246065
PMCPMC8896146
OpenAlexW4214810838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.